| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | di(2-ethylhexyl)phthalate 40.0 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN014_HEPG2_3H:F01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 | 6.88582 |
| CBR3 | carbonyl reductase 3 | 6.85554 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 5.18944 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.40688 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.3333 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.13243 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 4.04939 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.00203 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.89862 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.79981 |
| CYCS | cytochrome c, somatic | 3.71128 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.69379 |
| EPHB2 | EPH receptor B2 | 3.56579 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.18975 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 3.15033 |
| KIF14 | kinesin family member 14 | 2.77679 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.58886 |
| PCDHB11 | protocadherin beta 11 | 2.5646 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 2.52111 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.47619 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.43147 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 2.23664 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 2.13183 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.12653 |
| KIF20A | kinesin family member 20A | 2.09466 |
| NUP133 | nucleoporin 133kDa | 2.06778 |
| ATP4A | ATPase, H+/K+ exchanging, alpha polypeptide | 2.0469 |
| MIS18A | MIS18 kinetochore protein A | 2.0421 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -8.09878 |
| ZNF586 | zinc finger protein 586 | -7.07717 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -4.40063 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.0954 |
| TUBB6 | tubulin, beta 6 class V | -4.02739 |
| DSG2 | desmoglein 2 | -3.98518 |
| LDHD | lactate dehydrogenase D | -3.87152 |
| TRIB3 | tribbles pseudokinase 3 | -3.80092 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.65338 |
| DCK | deoxycytidine kinase | -3.5165 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.99909 |
| NGRN | neugrin, neurite outgrowth associated | -2.99323 |
| SNX11 | sorting nexin 11 | -2.90253 |
| TLCD3A | TLC domain containing 3A | -2.61661 |
| HSPB1 | heat shock 27kDa protein 1 | -2.58599 |
| TMEM267 | transmembrane protein 267 | -2.39843 |
| TCTN1 | tectonic family member 1 | -2.34988 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.342 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -2.33962 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.3374 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.28227 |
| ATG14 | autophagy related 14 | -2.16428 |
| EGF | epidermal growth factor | -2.13251 |
| MYO18A | myosin XVIIIA | -2.11044 |
| PRAF2 | PRA1 domain family, member 2 | -2.07927 |
| CPT1B | carnitine palmitoyltransferase 1B (muscle) | -2.07921 |
| FAIM | Fas apoptotic inhibitory molecule | -2.05814 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | -2.04998 |
| TRIP4 | thyroid hormone receptor interactor 4 | -2.03451 |
| LONP2 | lon peptidase 2, peroxisomal | -2.01701 |
