CRCGN014_HEPG2_3H:F02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methyl parathion 40.0 um perturbation at 3 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

104 genes differentially expressed following the CRCGN014_HEPG2_3H:F02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SFTPB surfactant protein B 5.54747
PPARG peroxisome proliferator-activated receptor gamma 5.27074
CIAO3 cytosolic iron-sulfur assembly component 3 5.0117
CYCS cytochrome c, somatic 4.92017
INTS3 integrator complex subunit 3 4.81431
STK10 serine/threonine kinase 10 4.65712
EVL Enah/Vasp-like 4.37775
MYLK myosin light chain kinase 4.31305
LCN2 lipocalin 2 4.1453
ADRB2 adrenoceptor beta 2, surface 4.06811
TRIM13 tripartite motif containing 13 4.0125
AMDHD2 amidohydrolase domain containing 2 3.96833
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.95369
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 3.85581
BZW2 basic leucine zipper and W2 domains 2 3.82214
PHKA1 phosphorylase kinase, alpha 1 (muscle) 3.66952
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 3.23104
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.08157
MEST mesoderm specific transcript 3.04912
TEX10 testis expressed 10 3.03436
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.97398
FZD7 frizzled class receptor 7 2.88273
ZBTB18 zinc finger and BTB domain containing 18 2.58325
LIN7B lin-7 homolog B (C. elegans) 2.55525
CHN1 chimerin 1 2.53357
SOX14 SRY (sex determining region Y)-box 14 2.5213
CPLX2 complexin 2 2.50375
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.50049
PYGO1 pygopus family PHD finger 1 2.45752
MTNAP1 mitochondrial nucleoid associated protein 1 2.43483
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 2.41045
MTNR1B melatonin receptor 1B 2.36212
PID1 phosphotyrosine interaction domain containing 1 2.35284
CD101 CD101 molecule 2.34582
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 2.33772
PKN1 protein kinase N1 2.28322
OR3A1 olfactory receptor, family 3, subfamily A, member 1 2.28268
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 2.26216
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.24191
GZMK granzyme K (granzyme 3; tryptase II) 2.23937
C5AR2 complement component 5a receptor 2 2.23292
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 2.22868
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2.22786
PKD2L2 polycystic kidney disease 2-like 2 2.21249
ACOXL acyl-CoA oxidase-like 2.20271
SORBS3 sorbin and SH3 domain containing 3 2.18988
CCR6 chemokine (C-C motif) receptor 6 2.18386
IFNA2 interferon, alpha 2 2.18227
NTN3 netrin 3 2.16901
ZNF208 zinc finger protein 208 2.14079
H2BC17 H2B clustered histone 17 2.14026
THAP12 THAP domain containing 12 2.13972
DAND5 DAN domain family member 5, BMP antagonist 2.13777
ADRA1B adrenoceptor alpha 1B 2.13017
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.12959
ANKRD40CL ANKRD40 C-terminal like 2.12899
KRT20 keratin 20, type I 2.12744
MLNR motilin receptor 2.12498
PCDHGA11 protocadherin gamma subfamily A, 11 2.11916
OR2J2 olfactory receptor, family 2, subfamily J, member 2 2.11618
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 2.11423
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1 2.1132
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 2.11166
OTUD7B OTU deubiquitinase 7B 2.09331
MCF2 MCF.2 cell line derived transforming sequence 2.08685
ZBTB7C zinc finger and BTB domain containing 7C 2.08634
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 2.07797
RFXAP regulatory factor X-associated protein 2.07666
POU6F2 POU class 6 homeobox 2 2.07196
CRX cone-rod homeobox 2.06288
ARSA arylsulfatase A 2.05574
THNSL1 threonine synthase-like 1 (S. cerevisiae) 2.05469
OPRK1 opioid receptor, kappa 1 2.05324
CCDC144A coiled-coil domain containing 144A 2.04993
RSF1 remodeling and spacing factor 1 2.04904
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.0468
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 2.04328
CABP5 calcium binding protein 5 2.03227
IMPG1 interphotoreceptor matrix proteoglycan 1 2.02955
PBOV1 prostate and breast cancer overexpressed 1 2.02372
KLRB1 killer cell lectin-like receptor subfamily B, member 1 2.01965
EFNB1 ephrin-B1 2.01621
FBXO24 F-box protein 24 2.00243

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -10.0
ADI1 acireductone dioxygenase 1 -4.75702
PRPF4 pre-mRNA processing factor 4 -4.5462
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.46232
LDHD lactate dehydrogenase D -4.44819
VAT1 vesicle amine transport 1 -4.43265
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.40359
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.20276
C2CD5 C2 calcium-dependent domain containing 5 -4.15573
COG2 component of oligomeric golgi complex 2 -4.12666
FBXO7 F-box protein 7 -4.01
CCNB2 cyclin B2 -3.97477
SNX11 sorting nexin 11 -3.48093
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.40356
EIF5 eukaryotic translation initiation factor 5 -3.16929
TRIB3 tribbles pseudokinase 3 -2.67321
MACF1 microtubule-actin crosslinking factor 1 -2.66956
TLCD3A TLC domain containing 3A -2.6014
CLTB clathrin, light chain B -2.26126
OXA1L oxidase (cytochrome c) assembly 1-like -2.14796
SNX5 sorting nexin 5 -2.01879