CRCGN014_HEPG2_3H:F03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description budesonide 21.37 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

623 genes differentially expressed following the CRCGN014_HEPG2_3H:F03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCDC85B coiled-coil domain containing 85B 6.65086
NR1H2 nuclear receptor subfamily 1, group H, member 2 6.18607
NANOS3 nanos homolog 3 (Drosophila) 6.1783
IDE insulin-degrading enzyme 6.00037
CXCL2 chemokine (C-X-C motif) ligand 2 5.84946
KIFBP kinesin family binding protein 5.82182
PPARG peroxisome proliferator-activated receptor gamma 5.75186
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 5.31024
TGFB3 transforming growth factor, beta 3 5.16069
TAC4 tachykinin 4 (hemokinin) 5.15647
OXCT1 3-oxoacid CoA transferase 1 5.09756
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.02879
C2CD2 C2 calcium-dependent domain containing 2 4.95023
STK10 serine/threonine kinase 10 4.82573
TIMP2 TIMP metallopeptidase inhibitor 2 4.78836
LYN LYN proto-oncogene, Src family tyrosine kinase 4.56562
BACE2 beta-site APP-cleaving enzyme 2 4.49652
EPHB2 EPH receptor B2 4.48814
ALDOC aldolase C, fructose-bisphosphate 4.39039
INTS3 integrator complex subunit 3 4.38655
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.32328
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 4.31655
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 4.26472
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.17745
LPAR2 lysophosphatidic acid receptor 2 4.16236
MCOLN1 mucolipin 1 4.11889
ANO10 anoctamin 10 4.08651
MUC1 mucin 1, cell surface associated 4.08585
IGFBP3 insulin-like growth factor binding protein 3 4.07703
HDGFL3 HDGF like 3 4.06082
SNAP25 synaptosomal-associated protein, 25kDa 4.05924
MYLK myosin light chain kinase 4.01355
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.93461
SQOR sulfide quinone oxidoreductase 3.91464
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.91137
MINDY1 MINDY lysine 48 deubiquitinase 1 3.90538
MNMIP1 manchette microtubule inner protein 1 3.86343
STAT5B signal transducer and activator of transcription 5B 3.85424
FZD7 frizzled class receptor 7 3.76173
TIAM1 T-cell lymphoma invasion and metastasis 1 3.73764
CHMP6 charged multivesicular body protein 6 3.69056
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 3.6686
ADGRE5 adhesion G protein-coupled receptor E5 3.6562
KIF5C kinesin family member 5C 3.65018
OPLAH 5-oxoprolinase (ATP-hydrolysing) 3.41751
HIC1 hypermethylated in cancer 1 3.40525
RPL39L ribosomal protein L39-like 3.37511
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.33264
AXIN1 axin 1 3.33102
MSRA methionine sulfoxide reductase A 3.32579
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 3.28656
BDH1 3-hydroxybutyrate dehydrogenase, type 1 3.2822
TRAK2 trafficking protein, kinesin binding 2 3.23751
PIH1D1 PIH1 domain containing 1 3.23365
GPC1 glypican 1 3.23035
KYAT3 kynurenine aminotransferase 3 3.19934
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 3.1815
TRPM4 transient receptor potential cation channel, subfamily M, member 4 3.15619
CEND1 cell cycle exit and neuronal differentiation 1 3.15535
CEP57 centrosomal protein 57kDa 3.13713
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 3.1306
SYCP2 synaptonemal complex protein 2 3.1288
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 3.12442
GPR162 G protein-coupled receptor 162 3.11398
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 3.08414
PNKP polynucleotide kinase 3'-phosphatase 3.07918
FAM20B family with sequence similarity 20, member B 3.06877
FCHO1 FCH domain only 1 3.06694
HOXA10 homeobox A10 3.0575
NSG2 neuronal vesicle trafficking associated 2 3.05356
STUM stum, mechanosensory transduction mediator homolog 3.04691
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 3.04683
FST follistatin 3.03808
PRDM8 PR domain containing 8 3.03101
CCKBR cholecystokinin B receptor 3.0023
RAX retina and anterior neural fold homeobox 2.98583
KIAA0513 KIAA0513 2.9721
PRLH prolactin releasing hormone 2.95552
FOLR3 folate receptor 3 (gamma) 2.94921
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 2.94418
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.93614
IL37 interleukin 37 2.92801
PRKX protein kinase, X-linked 2.91957
PLD3 phospholipase D family, member 3 2.91677
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.91248
GMIP GEM interacting protein 2.9072
ADRB2 adrenoceptor beta 2, surface 2.89508
GATA3 GATA binding protein 3 2.89288
NFIL3 nuclear factor, interleukin 3 regulated 2.88914
GPR15 G protein-coupled receptor 15 2.8794
DGAT1 diacylglycerol O-acyltransferase 1 2.87547
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 2.86766
HOOK2 hook microtubule-tethering protein 2 2.86349
SMG6 SMG6 nonsense mediated mRNA decay factor 2.84409
DRD5 dopamine receptor D5 2.83711
CAPN11 calpain 11 2.82988
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.82015
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 2.8127
S100A5 S100 calcium binding protein A5 2.80551
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 2.78118
CYTH3 cytohesin 3 2.76634
PPARD peroxisome proliferator-activated receptor delta 2.7641
C1QL1 complement component 1, q subcomponent-like 1 2.76385
TG thyroglobulin 2.76306
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.75672
C15ORF38-AP3S2 C15orf38-AP3S2 readthrough 2.75562
ADNP activity-dependent neuroprotector homeobox 2.73771
PSG5 pregnancy specific beta-1-glycoprotein 5 2.72577
BTK Bruton agammaglobulinemia tyrosine kinase 2.71831
PRSS2 protease, serine, 2 (trypsin 2) 2.71119
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.71047
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.70696
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.69961
PFKL phosphofructokinase, liver 2.68386
MAMLD1 mastermind-like domain containing 1 2.68308
DNASE1L2 deoxyribonuclease I-like 2 2.67167
PEX11A peroxisomal biogenesis factor 11 alpha 2.67013
WBP1L WW domain binding protein 1-like 2.66895
NGF nerve growth factor (beta polypeptide) 2.66879
FBN2 fibrillin 2 2.65507
CTF1 cardiotrophin 1 2.65473
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 2.65269
MAP7 microtubule-associated protein 7 2.65229
CLDN9 claudin 9 2.64299
CAPN1 calpain 1, (mu/I) large subunit 2.63802
ARMCX2 armadillo repeat containing, X-linked 2 2.61774
NSD3 nuclear receptor binding SET domain protein 3 2.61737
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.60167
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.60164
WNT5B wingless-type MMTV integration site family, member 5B 2.60042
GALR2 galanin receptor 2 2.59854
NID2 nidogen 2 (osteonidogen) 2.59073
STMN2 stathmin 2 2.58472
IL5 interleukin 5 2.5845
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 2.58245
DOC2B double C2-like domains, beta 2.58069
INSIG1 insulin induced gene 1 2.57354
FOXD2 forkhead box D2 2.57028
ANO1 anoctamin 1, calcium activated chloride channel 2.56279
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.55223
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.5472
SOX17 SRY (sex determining region Y)-box 17 2.54575
CLUL1 clusterin-like 1 (retinal) 2.54389
RND2 Rho family GTPase 2 2.54185
MIDEAS mitotic deacetylase associated SANT domain protein 2.53976
SDCBP syndecan binding protein (syntenin) 2.53789
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 2.53644
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.52881
EXTL1 exostosin-like glycosyltransferase 1 2.52747
GPR27 G protein-coupled receptor 27 2.52377
TJP3 tight junction protein 3 2.51504
RECK reversion-inducing-cysteine-rich protein with kazal motifs 2.51461
FMNL1 formin-like 1 2.51287
FOXH1 forkhead box H1 2.50017
MACO1 macoilin 1 2.49545
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 2.49418
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.48805
TBC1D10C TBC1 domain family, member 10C 2.48151
PRKCH protein kinase C, eta 2.4813
ZBTB18 zinc finger and BTB domain containing 18 2.47943
H2BC12 H2B clustered histone 12 2.47383
NEUROG3 neurogenin 3 2.47295
CRTAP cartilage associated protein 2.47294
ANGPTL2 angiopoietin-like 2 2.47274
UNC5C unc-5 homolog C (C. elegans) 2.47238
POU2F2 POU class 2 homeobox 2 2.47079
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 2.45819
HAPLN2 hyaluronan and proteoglycan link protein 2 2.45186
IRF5 interferon regulatory factor 5 2.45153
LIPF lipase, gastric 2.45058
REM1 RAS (RAD and GEM)-like GTP-binding 1 2.44911
FSHR follicle stimulating hormone receptor 2.44855
PRKCE protein kinase C, epsilon 2.44731
LOC128966586 pepsin A-4-like 2.44709
SFRP1 secreted frizzled-related protein 1 2.44698
CLDN15 claudin 15 2.44381
PER3 period circadian clock 3 2.44335
EHMT1 euchromatic histone-lysine N-methyltransferase 1 2.44052
LOC107985101 uncharacterized LOC107985101 2.43956
PARP1 poly (ADP-ribose) polymerase 1 2.4372
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 2.43703
CDHR1 cadherin-related family member 1 2.4339
AANAT aralkylamine N-acetyltransferase 2.43185
H2BC11 H2B clustered histone 11 2.42742
GUCY2F guanylate cyclase 2F, retinal 2.41781
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.41305
MXRA5 matrix-remodelling associated 5 2.41249
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 2.40656
NTN3 netrin 3 2.40293
MUC2 mucin 2, oligomeric mucus/gel-forming 2.40004
PRSS58 protease, serine, 58 2.39355
GSTZ1 glutathione S-transferase zeta 1 2.3895
ERBB3 erb-b2 receptor tyrosine kinase 3 2.38729
C2CD2L C2CD2-like 2.3848
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 2.38224
DNAAF3 dynein, axonemal, assembly factor 3 2.37904
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 2.37607
HHAT hedgehog acyltransferase 2.37538
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 2.3742
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 2.37259
CSN1S1 casein alpha s1 2.37214
TLX2 T-cell leukemia homeobox 2 2.3711
GAN gigaxonin 2.37087
ABHD4 abhydrolase domain containing 4 2.36847
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 2.36773
MST1R macrophage stimulating 1 receptor 2.3673
GDF11 growth differentiation factor 11 2.36682
CGGBP1 CGG triplet repeat binding protein 1 2.36637
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.3662
PTAFR platelet-activating factor receptor 2.36587
MAP9 microtubule-associated protein 9 2.36247
CPLX3 complexin 3 2.35972
FUT2 fucosyltransferase 2 (secretor status included) 2.35797
IL13 interleukin 13 2.35661
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 2.35316
GLI2 GLI family zinc finger 2 2.34913
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.34349
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 2.34104
PDIA5 protein disulfide isomerase family A, member 5 2.33967
TASL TLR adaptor interacting with endolysosomal SLC15A4 2.33922
YBX2 Y box binding protein 2 2.33666
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 2.33288
NEUROD4 neuronal differentiation 4 2.33232
OR3A3 olfactory receptor, family 3, subfamily A, member 3 2.32889
TSKS testis-specific serine kinase substrate 2.32536
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.3193
TREM1 triggering receptor expressed on myeloid cells 1 2.31884
PDZD7 PDZ domain containing 7 2.3185
RAB27B RAB27B, member RAS oncogene family 2.3167
BAMBI BMP and activin membrane-bound inhibitor 2.31258
ADGRF1 adhesion G protein-coupled receptor F1 2.31005
SYTL2 synaptotagmin-like 2 2.30937
IQCC IQ motif containing C 2.30626
AQP7 aquaporin 7 2.30342
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.30292
SIGLEC8 sialic acid binding Ig-like lectin 8 2.29982
INPP5J inositol polyphosphate-5-phosphatase J 2.29725
TAOK3 TAO kinase 3 2.2925
ELAVL3 ELAV like neuron-specific RNA binding protein 3 2.28996
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.28991
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 2.28952
ATP5IF1 ATP synthase inhibitory factor subunit 1 2.28833
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.28541
OSBPL7 oxysterol binding protein-like 7 2.28483
COQ8A coenzyme Q8A 2.28262
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 2.28092
ATP4B ATPase, H+/K+ exchanging, beta polypeptide 2.28064
NUCB2 nucleobindin 2 2.27929
SIGLEC15 sialic acid binding Ig-like lectin 15 2.27437
ATG2A autophagy related 2A 2.27315
BMPR1A bone morphogenetic protein receptor, type IA 2.27058
FGF23 fibroblast growth factor 23 2.27009
SH3BP1 SH3-domain binding protein 1 2.26951
RIMS1 regulating synaptic membrane exocytosis 1 2.26943
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 2.26851
VWA7 von Willebrand factor A domain containing 7 2.26598
PSKH1 protein serine kinase H1 2.26418
TRIM11 tripartite motif containing 11 2.26017
CCNO cyclin O 2.25965
MYO16 myosin XVI 2.25415
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.25178
REC8 REC8 meiotic recombination protein 2.25154
GPR85 G protein-coupled receptor 85 2.24999
LIPE lipase, hormone-sensitive 2.24677
ZNF219 zinc finger protein 219 2.24461
JRKL JRK-like 2.23848
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.23355
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 2.23263
CLCN1 chloride channel, voltage-sensitive 1 2.23001
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 2.2292
DMRT1 doublesex and mab-3 related transcription factor 1 2.22651
ATXN3L ataxin 3-like 2.22494
FOXN1 forkhead box N1 2.22476
GSTM3 glutathione S-transferase mu 3 (brain) 2.22464
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 2.223
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 2.21115
KAT6A K(lysine) acetyltransferase 6A 2.21101
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 2.20975
CORO7-PAM16 CORO7-PAM16 readthrough 2.20904
LIPG lipase, endothelial 2.20516
PLIN1 perilipin 1 2.2045
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 2.2038
PLP1 proteolipid protein 1 2.20245
SGSH N-sulfoglucosamine sulfohydrolase 2.20209
KIRREL1 kirre like nephrin family adhesion molecule 1 2.20034
PRSS3 protease, serine, 3 2.19972
ZNF205 zinc finger protein 205 2.19819
WNT7A wingless-type MMTV integration site family, member 7A 2.19627
THBS4 thrombospondin 4 2.19606
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2.19604
FAM163A family with sequence similarity 163, member A 2.19358
ADGRD2 adhesion G protein-coupled receptor D2 2.19326
PLCD1 phospholipase C, delta 1 2.19302
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.19284
LEP leptin 2.19163
PSG9 pregnancy specific beta-1-glycoprotein 9 2.19096
LRRN3 leucine rich repeat neuronal 3 2.1897
THBD thrombomodulin 2.18896
VASP vasodilator-stimulated phosphoprotein 2.18822
CCND3 cyclin D3 2.18785
TNN tenascin N 2.18683
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 2.18562
SIPA1L1 signal-induced proliferation-associated 1 like 1 2.18047
MTNAP1 mitochondrial nucleoid associated protein 1 2.17971
TMEM209 transmembrane protein 209 2.17755
GBA1 glucosylceramidase beta 1 2.17658
ERCC6 excision repair cross-complementation group 6 2.17658
ZNF528 zinc finger protein 528 2.17553
SYNGR3 synaptogyrin 3 2.17416
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.17236
A4GNT alpha-1,4-N-acetylglucosaminyltransferase 2.17219
FSCN2 fascin actin-bundling protein 2, retinal 2.17212
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 2.1713
MSANTD3-TMEFF1 MSANTD3-TMEFF1 readthrough 2.16824
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 2.16749
MAGEL2 melanoma antigen family L2 2.16662
PCDHB1 protocadherin beta 1 2.16473
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.16426
HOXB1 homeobox B1 2.16322
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 2.16145
PRR3 proline rich 3 2.1606
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 2.15798
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.15766
NUP107 nucleoporin 107kDa 2.15718
CPQ carboxypeptidase Q 2.15494
MRC2 mannose receptor, C type 2 2.15301
EVC Ellis van Creveld protein 2.15129
NLGN4Y neuroligin 4, Y-linked 2.15109
CNTN2 contactin 2 (axonal) 2.14574
PKN1 protein kinase N1 2.14559
CDX1 caudal type homeobox 1 2.14473
BCOR BCL6 corepressor 2.14425
PTPRN protein tyrosine phosphatase, receptor type, N 2.14352
CHIA chitinase, acidic 2.14277
H2BC15 H2B clustered histone 15 2.14181
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.14055
PLCH2 phospholipase C, eta 2 2.13971
SPHK2 sphingosine kinase 2 2.1389
FTH1 ferritin, heavy polypeptide 1 2.13818
CNTN6 contactin 6 2.13564
TEC tec protein tyrosine kinase 2.12942
MYO1A myosin IA 2.12628
ERBB4 erb-b2 receptor tyrosine kinase 4 2.12622
PSG4 pregnancy specific beta-1-glycoprotein 4 2.12493
EFCAB14 EF-hand calcium binding domain 14 2.12398
EBF2 early B-cell factor 2 2.1203
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.11774
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 2.11461
AMHR2 anti-Mullerian hormone receptor, type II 2.11121
FZD8 frizzled class receptor 8 2.10982
LHCGR luteinizing hormone/choriogonadotropin receptor 2.10847
NAGLU N-acetylglucosaminidase, alpha 2.10764
LCE2B late cornified envelope 2B 2.10712
CTSK cathepsin K 2.10693
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.1062
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 2.10374
RASIP1 Ras interacting protein 1 2.10291
VAX2 ventral anterior homeobox 2 2.1013
MAB21L1 mab-21-like 1 (C. elegans) 2.09948
TSHR thyroid stimulating hormone receptor 2.09853
VENTX VENT homeobox 2.09554
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.09465
NR4A1 nuclear receptor subfamily 4, group A, member 1 2.09448
PPCS phosphopantothenoylcysteine synthetase 2.09138
INSL4 insulin-like 4 (placenta) 2.09065
JMJD4 jumonji domain containing 4 2.09022
OR1E1 olfactory receptor, family 1, subfamily E, member 1 2.08961
PLEKHA6 pleckstrin homology domain containing, family A member 6 2.08919
IGF2 insulin-like growth factor 2 2.08872
GTF2IRD2B GTF2I repeat domain containing 2B 2.08498
MDM4 MDM4, p53 regulator 2.0835
SSX2 synovial sarcoma, X breakpoint 2 2.07996
CASS4 Cas scaffolding protein family member 4 2.07894
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 2.07795
EPAS1 endothelial PAS domain protein 1 2.0772
PSG6 pregnancy specific beta-1-glycoprotein 6 2.07684
SYNE2 spectrin repeat containing, nuclear envelope 2 2.0745
HOXA2 homeobox A2 2.07279
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 2.0721
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.06783
BACE1 beta-site APP-cleaving enzyme 1 2.06525
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.06523
MTM1 myotubularin 1 2.06477
GLI3 GLI family zinc finger 3 2.06145
FEV FEV (ETS oncogene family) 2.06067
H2AC7 H2A clustered histone 7 2.05859
PRKG2 protein kinase, cGMP-dependent, type II 2.05777
SGMS1 sphingomyelin synthase 1 2.05689
GAS6 growth arrest-specific 6 2.05562
TTLL3 tubulin tyrosine ligase-like family member 3 2.05325
FAT2 FAT atypical cadherin 2 2.05022
BMP8B bone morphogenetic protein 8b 2.04944
BEST2 bestrophin 2 2.04703
CNTFR ciliary neurotrophic factor receptor 2.04702
ZNF254 zinc finger protein 254 2.04675
CA5B carbonic anhydrase VB, mitochondrial 2.04595
H2BC3 H2B clustered histone 3 2.04403
GSTK1 glutathione S-transferase kappa 1 2.04365
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 2.04356
CLDN14 claudin 14 2.04291
TPO thyroid peroxidase 2.04198
HROB homologous recombination factor with OB-fold 2.04193
TSPO2 translocator protein 2 2.0381
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 2.03749
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 2.03618
POM121L2 POM121 transmembrane nucleoporin-like 2 2.03525
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.03316
LBHD1 LBH domain containing 1 2.03297
SLC22A17 solute carrier family 22, member 17 2.03201
TEF thyrotrophic embryonic factor 2.03146
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 2.02986
SOX21 SRY (sex determining region Y)-box 21 2.02821
CAPN6 calpain 6 2.02478
TNPO3 transportin 3 2.02457
PHACTR4 phosphatase and actin regulator 4 2.02248
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 2.02246
NABP1 nucleic acid binding protein 1 2.02241
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 2.02176
PCDHB11 protocadherin beta 11 2.02091
MATN4 matrilin 4 2.02053
GPR20 G protein-coupled receptor 20 2.01997
MMP24OS MMP24 opposite strand 2.01948
SERGEF secretion regulating guanine nucleotide exchange factor 2.01751
EXOC6B exocyst complex component 6B 2.01586
SLIT3 slit homolog 3 (Drosophila) 2.01432
DGKB diacylglycerol kinase, beta 90kDa 2.01406
EMC9 ER membrane protein complex subunit 9 2.01389
MCTP2 multiple C2 domains, transmembrane 2 2.01361
RIN1 Ras and Rab interactor 1 2.01355
USP6NL USP6 N-terminal like 2.01202
ZNF623 zinc finger protein 623 2.01123
CAPN5 calpain 5 2.01106
F2RL2 coagulation factor II (thrombin) receptor-like 2 2.01001
ADAM29 ADAM metallopeptidase domain 29 2.0092
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 2.00902
SPIDR scaffolding protein involved in DNA repair 2.00867
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 2.00809
FOXO3 forkhead box O3 2.00772
CREM cAMP responsive element modulator 2.00771
LALBA lactalbumin, alpha- 2.00735
WIPF1 WAS/WASL interacting protein family, member 1 2.00714
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.00657
SETD1A SET domain containing 1A 2.00579

decreased expression

Symbol Name Standardized Value
ZNF586 zinc finger protein 586 -8.43036
ISOC1 isochorismatase domain containing 1 -7.53246
ARID5B AT rich interactive domain 5B (MRF1-like) -7.52333
PCCB propionyl CoA carboxylase, beta polypeptide -6.87534
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -5.73322
MRPS2 mitochondrial ribosomal protein S2 -4.90928
CASP7 caspase 7, apoptosis-related cysteine peptidase -4.85165
CD58 CD58 molecule -4.84763
GRWD1 glutamate-rich WD repeat containing 1 -4.81645
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.71087
SLC35F2 solute carrier family 35, member F2 -4.67101
CAB39 calcium binding protein 39 -4.61344
SPAG4 sperm associated antigen 4 -4.52723
PCNA proliferating cell nuclear antigen -4.3295
C2CD5 C2 calcium-dependent domain containing 5 -4.31745
TSEN2 TSEN2 tRNA splicing endonuclease subunit -4.27069
CASP3 caspase 3, apoptosis-related cysteine peptidase -4.23663
GTPBP8 GTP-binding protein 8 (putative) -4.13693
ACAA1 acetyl-CoA acyltransferase 1 -4.1256
CD320 CD320 molecule -4.0801
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.03941
ZDHHC6 zinc finger, DHHC-type containing 6 -3.94639
ADI1 acireductone dioxygenase 1 -3.86651
RFC2 replication factor C (activator 1) 2, 40kDa -3.83945
TLCD3A TLC domain containing 3A -3.82982
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.79115
PRPF4 pre-mRNA processing factor 4 -3.77042
NCK1 NCK adaptor protein 1 -3.6963
LGMN legumain -3.55701
RPIA ribose 5-phosphate isomerase A -3.45107
MVP major vault protein -3.44749
FOXJ3 forkhead box J3 -3.42331
TPD52L2 tumor protein D52-like 2 -3.39646
PARP2 poly (ADP-ribose) polymerase 2 -3.34987
KDM3A lysine (K)-specific demethylase 3A -3.30004
PMPCA peptidase (mitochondrial processing) alpha -3.28805
YBX3 Y box binding protein 3 -3.21328
TXNDC9 thioredoxin domain containing 9 -3.17967
REEP5 receptor accessory protein 5 -3.16458
TERT telomerase reverse transcriptase -3.14632
ANKRD10 ankyrin repeat domain 10 -3.14476
TCTN1 tectonic family member 1 -3.1259
FGFR4 fibroblast growth factor receptor 4 -3.04516
MB myoglobin -3.03363
FAIM Fas apoptotic inhibitory molecule -3.01057
UFM1 ubiquitin-fold modifier 1 -3.0097
PTK7 protein tyrosine kinase 7 (inactive) -3.00629
RGS2 regulator of G-protein signaling 2 -3.00179
ENTR1 endosome associated trafficking regulator 1 -2.99753
CLTB clathrin, light chain B -2.98656
MAPK13 mitogen-activated protein kinase 13 -2.98331
PLS3 plastin 3 -2.97186
SNCA synuclein, alpha (non A4 component of amyloid precursor) -2.94367
PAEP progestagen-associated endometrial protein -2.82746
RNF11 ring finger protein 11 -2.81636
TBC1D4 TBC1 domain family, member 4 -2.81156
TP53BP2 tumor protein p53 binding protein 2 -2.79606
INTS13 integrator complex subunit 13 -2.79306
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.78762
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.78666
DERA deoxyribose-phosphate aldolase (putative) -2.76551
MORC4 MORC family CW-type zinc finger 4 -2.75786
MED27 mediator complex subunit 27 -2.74177
S100A8 S100 calcium binding protein A8 -2.73246
NIP7 NIP7, nucleolar pre-rRNA processing protein -2.72413
MACF1 microtubule-actin crosslinking factor 1 -2.71737
GAA glucosidase, alpha; acid -2.69365
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.69244
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -2.68486
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.67752
BMP4 bone morphogenetic protein 4 -2.67351
HAO2 hydroxyacid oxidase 2 (long chain) -2.67332
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.66546
CRNN cornulin -2.61021
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -2.60013
SINHCAF SIN3-HDAC complex associated factor -2.59038
TOR1A torsin family 1, member A (torsin A) -2.56782
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.55481
TCEAL4 transcription elongation factor A (SII)-like 4 -2.54419
UBAC1 UBA domain containing 1 -2.53182
CHPF chondroitin polymerizing factor -2.51796
LOC124907782 dual specificity protein phosphatase 22 -2.5088
FASTKD5 FAST kinase domains 5 -2.48893
TXNL4B thioredoxin-like 4B -2.48669
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -2.48187
TTC19 tetratricopeptide repeat domain 19 -2.47329
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) -2.47145
SNCAIP synuclein, alpha interacting protein -2.46829
GCC2 GRIP and coiled-coil domain containing 2 -2.46411
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.45928
MECR mitochondrial trans-2-enoyl-CoA reductase -2.44122
IST1 increased sodium tolerance 1 homolog (yeast) -2.43983
CCNA1 cyclin A1 -2.42202
SACS sacsin molecular chaperone -2.41571
ZW10 zw10 kinetochore protein -2.41542
BPHL biphenyl hydrolase-like (serine hydrolase) -2.41369
LAPTM4A lysosomal protein transmembrane 4 alpha -2.41326
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -2.40828
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) -2.40361
H2AB2 H2A.B variant histone 2 -2.37222
ICAM1 intercellular adhesion molecule 1 -2.371
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -2.36286
IL32 interleukin 32 -2.36168
MDN1 MDN1, midasin homolog (yeast) -2.35839
UBE2A ubiquitin-conjugating enzyme E2A -2.33972
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.33631
TATDN2 TatD DNase domain containing 2 -2.3158
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -2.31052
PHF2 PHD finger protein 2 -2.31036
SRPRB signal recognition particle receptor, B subunit -2.30566
IRGQ immunity-related GTPase family, Q -2.29856
VKORC1 vitamin K epoxide reductase complex, subunit 1 -2.29776
IPO13 importin 13 -2.29644
NISCH nischarin -2.28528
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 -2.28447
NOP16 NOP16 nucleolar protein -2.27319
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -2.27176
ABI1 abl-interactor 1 -2.25369
DCK deoxycytidine kinase -2.24988
LYPLA1 lysophospholipase I -2.24925
ELAC2 elaC ribonuclease Z 2 -2.24892
ANAPC2 anaphase promoting complex subunit 2 -2.24733
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 -2.24002
SESN1 sestrin 1 -2.23882
RPP40 ribonuclease P/MRP 40kDa subunit -2.23116
SEC16A SEC16 homolog A (S. cerevisiae) -2.22897
VCAM1 vascular cell adhesion molecule 1 -2.22645
PWP1 PWP1 homolog (S. cerevisiae) -2.2224
ARL5A ADP-ribosylation factor-like 5A -2.20966
SRFBP1 serum response factor binding protein 1 -2.20253
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.20028
ZNF304 zinc finger protein 304 -2.19659
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 -2.19381
SMPX small muscle protein, X-linked -2.1738
CDK1 cyclin-dependent kinase 1 -2.17004
CST1 cystatin SN -2.16638
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 -2.15897
ZHX2 zinc fingers and homeoboxes 2 -2.15788
PPP1R3C protein phosphatase 1, regulatory subunit 3C -2.14802
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -2.14628
LMAN2L lectin, mannose-binding 2-like -2.14555
REEP1 receptor accessory protein 1 -2.14527
TMEM11 transmembrane protein 11 -2.14135
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) -2.13626
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -2.13501
CDK5RAP1 CDK5 regulatory subunit associated protein 1 -2.12776
DYNLT3 dynein, light chain, Tctex-type 3 -2.12601
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -2.126
ABHD10 abhydrolase domain containing 10 -2.12333
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -2.11996
MAOB monoamine oxidase B -2.11996
MCM5 minichromosome maintenance complex component 5 -2.11622
TUSC2 tumor suppressor candidate 2 -2.11
MRPL34 mitochondrial ribosomal protein L34 -2.10707
NR1H4 nuclear receptor subfamily 1, group H, member 4 -2.09659
HDAC3 histone deacetylase 3 -2.08671
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.0861
SHROOM2 shroom family member 2 -2.08294
LIAS lipoic acid synthetase -2.07721
CNPY3 canopy FGF signaling regulator 3 -2.07404
UIMC1 ubiquitin interaction motif containing 1 -2.0715
MYDGF myeloid-derived growth factor -2.07002
PTPN6 protein tyrosine phosphatase, non-receptor type 6 -2.06977
FOS FBJ murine osteosarcoma viral oncogene homolog -2.06868
MAP2K5 mitogen-activated protein kinase kinase 5 -2.06768
BABAM1 BRISC and BRCA1 A complex member 1 -2.06301
TDG thymine-DNA glycosylase -2.06022
EXOSC5 exosome component 5 -2.0591
CDC25B cell division cycle 25B -2.04281
ADORA2B adenosine A2b receptor -2.03635
FBXO7 F-box protein 7 -2.03319
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.03101
DCP2 decapping mRNA 2 -2.02816
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.01992
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -2.01441
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.01047
TBC1D31 TBC1 domain family, member 31 -2.00534
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 -2.0036
SH3GLB1 SH3-domain GRB2-like endophilin B1 -2.00177
TBX2 T-box 2 -2.00174