CRCGN014_HEPG2_3H:F04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ethyl alcohol 42.4 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN014_HEPG2_3H:F04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 7.80066
KLHL21 kelch-like family member 21 5.10106
BACE2 beta-site APP-cleaving enzyme 2 5.04542
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 5.00789
UBQLN2 ubiquilin 2 4.98421
DIPK1A divergent protein kinase domain 1A 4.2707
HOXA10 homeobox A10 3.73621
CHMP6 charged multivesicular body protein 6 3.61931
BZW2 basic leucine zipper and W2 domains 2 3.43145
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.83097
SKIC8 SKI8 subunit of superkiller complex 2.74817
ADGRE5 adhesion G protein-coupled receptor E5 2.4442
LCN2 lipocalin 2 2.30118
ECT2 epithelial cell transforming 2 2.25998
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.25681
CSK c-src tyrosine kinase 2.2555
RBL1 retinoblastoma-like 1 2.21803
SCCPDH saccharopine dehydrogenase (putative) 2.17168
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 2.13941
IFT81 intraflagellar transport 81 2.06365
HOXA10-HOXA9 HOXA10-HOXA9 readthrough 2.02536

decreased expression

Symbol Name Standardized Value
GNAS GNAS complex locus -6.00275
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.86259
HMG20B high mobility group 20B -3.40837
NVL nuclear VCP-like -3.03233
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.96872
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.93319
LDHD lactate dehydrogenase D -2.89269
CDC20 cell division cycle 20 -2.72994
CCNB2 cyclin B2 -2.66262
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.51728
ZNF586 zinc finger protein 586 -2.51243
TES testin LIM domain protein -2.39945
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.25727
KRT18 keratin 18, type I -2.14922
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.04401