| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | kynurenic-acid 21.14 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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62 genes differentially expressed following the CRCGN014_HEPG2_3H:F05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 7.86116 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 5.2412 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 5.09335 |
| H2BC12 | H2B clustered histone 12 | 4.78977 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 4.5631 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.13599 |
| CHN1 | chimerin 1 | 3.93078 |
| NOTCH1 | notch 1 | 3.90537 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.85791 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.71603 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.69849 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.5971 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.37635 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.1009 |
| TEX10 | testis expressed 10 | 3.00317 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.70881 |
| CTTN | cortactin | 2.67443 |
| EGF | epidermal growth factor | 2.5692 |
| CCDC86 | coiled-coil domain containing 86 | 2.54232 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.45239 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 2.43495 |
| MAMLD1 | mastermind-like domain containing 1 | 2.43416 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 2.36398 |
| MAP7 | microtubule-associated protein 7 | 2.34002 |
| OLFML2A | olfactomedin-like 2A | 2.30224 |
| SLC25A46 | solute carrier family 25, member 46 | 2.29732 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 2.16951 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.14078 |
| MATN2 | matrilin 2 | 2.11591 |
| ACACB | acetyl-CoA carboxylase beta | 2.08821 |
| COL15A1 | collagen, type XV, alpha 1 | 2.08612 |
| EPHA3 | EPH receptor A3 | 2.05439 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 2.00297 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TLCD3A | TLC domain containing 3A | -7.05988 |
| DERA | deoxyribose-phosphate aldolase (putative) | -5.62833 |
| ZNF586 | zinc finger protein 586 | -5.56592 |
| ELAC2 | elaC ribonuclease Z 2 | -5.52703 |
| DNM1L | dynamin 1-like | -4.69102 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.77774 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.72351 |
| TP53BP2 | tumor protein p53 binding protein 2 | -3.68745 |
| PCNA | proliferating cell nuclear antigen | -3.65778 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.62791 |
| TLR4 | toll-like receptor 4 | -3.49391 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -3.20776 |
| SPAG4 | sperm associated antigen 4 | -3.17714 |
| CCNB2 | cyclin B2 | -3.08055 |
| TCERG1 | transcription elongation regulator 1 | -3.00601 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -2.98645 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.65565 |
| SLC12A9 | solute carrier family 12, member 9 | -2.51877 |
| TBC1D31 | TBC1 domain family, member 31 | -2.50184 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.31473 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.2804 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.26979 |
| CTC1 | CTS telomere maintenance complex component 1 | -2.22416 |
| IPO13 | importin 13 | -2.20515 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.16659 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -2.16491 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -2.06968 |
| DHPS | deoxyhypusine synthase | -2.06628 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.05669 |
