CRCGN014_HEPG2_3H:F06 Gene Set
Genes
46 genes differentially expressed following the CRCGN014_HEPG2_3H:F06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
9.2112
|
|
MAP7
|
microtubule-associated protein 7
|
6.71318
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
4.93493
|
|
SFTPB
|
surfactant protein B
|
4.93415
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
4.92754
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.49376
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
4.39058
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.17553
|
|
GATA3
|
GATA binding protein 3
|
4.12049
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.96307
|
|
MYLK
|
myosin light chain kinase
|
3.94664
|
|
PRKCH
|
protein kinase C, eta
|
3.73894
|
|
PTK2
|
protein tyrosine kinase 2
|
3.53222
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
3.33457
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
3.18843
|
|
SHB
|
Src homology 2 domain containing adaptor protein B
|
2.94949
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.63804
|
|
IDE
|
insulin-degrading enzyme
|
2.35031
|
|
BMP4
|
bone morphogenetic protein 4
|
2.28761
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.26546
|
|
EFCC1
|
EF-hand and coiled-coil domain containing 1
|
2.2112
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.19643
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
2.1935
|
|
THEM6
|
thioesterase superfamily member 6
|
2.19171
|
|
AQP3
|
aquaporin 3 (Gill blood group)
|
2.15193
|
|
ZNF750
|
zinc finger protein 750
|
2.13088
|
|
TACR2
|
tachykinin receptor 2
|
2.11515
|
|
ANO2
|
anoctamin 2, calcium activated chloride channel
|
2.02749
|
|
WNT7A
|
wingless-type MMTV integration site family, member 7A
|
2.00906
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-5.53369
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.48494
|
|
ZNF586
|
zinc finger protein 586
|
-4.81084
|
|
PLK1
|
polo-like kinase 1
|
-4.44934
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-4.3633
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.68978
|
|
CCNB2
|
cyclin B2
|
-3.55009
|
|
TBC1D31
|
TBC1 domain family, member 31
|
-3.50304
|
|
TLR4
|
toll-like receptor 4
|
-3.41033
|
|
GLOD4
|
glyoxalase domain containing 4
|
-3.07972
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.59213
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.538
|
|
NVL
|
nuclear VCP-like
|
-2.4687
|
|
DTYMK
|
deoxythymidylate kinase (thymidylate kinase)
|
-2.31632
|
|
GNG7
|
guanine nucleotide binding protein (G protein), gamma 7
|
-2.31192
|
|
GADD45GIP1
|
growth arrest and DNA-damage-inducible, gamma interacting protein 1
|
-2.10287
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.06501
|