CRCGN014_HEPG2_3H:F08 Gene Set
Genes
39 genes differentially expressed following the CRCGN014_HEPG2_3H:F08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
4.75628
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.9661
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
3.85124
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.66305
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.65593
|
|
HOXA10
|
homeobox A10
|
3.6288
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.31853
|
|
CTSL
|
cathepsin L
|
3.17751
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.13522
|
|
E2F2
|
E2F transcription factor 2
|
3.13378
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.97302
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.96176
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.93565
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.90412
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.89652
|
|
NOTCH1
|
notch 1
|
2.65487
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.57917
|
|
COG4
|
component of oligomeric golgi complex 4
|
2.52685
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
2.52499
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.49925
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.42425
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.3558
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.2494
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.18319
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.14748
|
|
CHEK2
|
checkpoint kinase 2
|
2.10811
|
|
EPN2
|
epsin 2
|
2.04467
|
|
COX6C
|
cytochrome c oxidase subunit VIc
|
2.02382
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-6.60384
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.95203
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.62703
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.98063
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.87394
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.81751
|
|
ZNF586
|
zinc finger protein 586
|
-2.72024
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.61873
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.1492
|
|
CCNB2
|
cyclin B2
|
-2.06062
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.0561
|
