CRCGN014_HEPG2_3H:F11 Gene Set
Genes
49 genes differentially expressed following the CRCGN014_HEPG2_3H:F11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CBR3
|
carbonyl reductase 3
|
5.98429
|
|
KIF14
|
kinesin family member 14
|
4.9086
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.97224
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.90971
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.80087
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.72658
|
|
CCNF
|
cyclin F
|
3.69218
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.64281
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.48535
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.03612
|
|
CHN1
|
chimerin 1
|
3.01168
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.93035
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.88257
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.76722
|
|
VGLL4
|
vestigial-like family member 4
|
2.59229
|
|
SKA1
|
spindle and kinetochore associated complex subunit 1
|
2.31055
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.26438
|
|
UBA6
|
ubiquitin-like modifier activating enzyme 6
|
2.11786
|
|
HIF1AN
|
hypoxia inducible factor 1, alpha subunit inhibitor
|
2.07975
|
|
IREB2
|
iron-responsive element binding protein 2
|
2.05007
|
|
DUSP3
|
dual specificity phosphatase 3
|
2.04552
|
|
CLOCK
|
clock circadian regulator
|
2.03108
|
|
S100A4
|
S100 calcium binding protein A4
|
2.02389
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-6.73948
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.563
|
|
LDHD
|
lactate dehydrogenase D
|
-6.52911
|
|
ZNF586
|
zinc finger protein 586
|
-5.77322
|
|
GNAS
|
GNAS complex locus
|
-4.80306
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.21186
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-3.60335
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.36315
|
|
VAT1
|
vesicle amine transport 1
|
-3.27323
|
|
THAP11
|
THAP domain containing 11
|
-3.17781
|
|
ENOPH1
|
enolase-phosphatase 1
|
-3.11219
|
|
ISOC1
|
isochorismatase domain containing 1
|
-3.11114
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.00211
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.89398
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.79476
|
|
CDC20
|
cell division cycle 20
|
-2.77768
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-2.75898
|
|
NVL
|
nuclear VCP-like
|
-2.44809
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.26436
|
|
CCNB2
|
cyclin B2
|
-2.26212
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.18402
|
|
EMC8
|
ER membrane protein complex subunit 8
|
-2.16896
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.16612
|
|
HMOX1
|
heme oxygenase 1
|
-2.12771
|
|
SNX11
|
sorting nexin 11
|
-2.00821
|
|
SMAP1
|
small ArfGAP 1
|
-2.00792
|
