CRCGN014_HEPG2_3H:F13 Gene Set
Genes
49 genes differentially expressed following the CRCGN014_HEPG2_3H:F13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
9.77171
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
6.84733
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
5.19608
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
5.05447
|
|
STIMATE
|
STIM activating enhancer
|
4.82924
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.37569
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.36939
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
3.6032
|
|
CSK
|
c-src tyrosine kinase
|
3.58793
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
3.32884
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.21984
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
3.04597
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.97987
|
|
FZD7
|
frizzled class receptor 7
|
2.82906
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.76731
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
2.69039
|
|
SAA2
|
serum amyloid A2
|
2.38809
|
|
LCN2
|
lipocalin 2
|
2.36673
|
|
LRRC42
|
leucine rich repeat containing 42
|
2.28601
|
|
HOXA10
|
homeobox A10
|
2.28554
|
|
STXBP2
|
syntaxin binding protein 2
|
2.22411
|
|
TBP
|
TATA box binding protein
|
2.19696
|
|
POLR3F
|
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
|
2.18514
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.16838
|
|
PLEKHB1
|
pleckstrin homology domain containing, family B (evectins) member 1
|
2.06892
|
|
PRL
|
prolactin
|
2.06784
|
|
TMEM231
|
transmembrane protein 231
|
2.0433
|
|
DNAI7
|
dynein axonemal intermediate chain 7
|
2.03663
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-6.87862
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.51648
|
|
HAT1
|
histone acetyltransferase 1
|
-4.41702
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-4.24961
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.04426
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.98655
|
|
LDHD
|
lactate dehydrogenase D
|
-3.28683
|
|
CCNB2
|
cyclin B2
|
-3.18657
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.07619
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.92928
|
|
BNIP3
|
BCL2/adenovirus E1B 19kDa interacting protein 3
|
-2.87333
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.77598
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.68336
|
|
WASHC4
|
WASH complex subunit 4
|
-2.61591
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.57365
|
|
PDZD2
|
PDZ domain containing 2
|
-2.50011
|
|
RNF167
|
ring finger protein 167
|
-2.49766
|
|
CCNB1
|
cyclin B1
|
-2.44815
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.35408
|
|
TRAPPC6A
|
trafficking protein particle complex 6A
|
-2.09979
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.02256
|
