CRCGN014_HEPG2_3H:F14 Gene Set
Genes
51 genes differentially expressed following the CRCGN014_HEPG2_3H:F14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
3.87162
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.70166
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.44522
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.25653
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.99397
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.92979
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.65129
|
|
MAP7
|
microtubule-associated protein 7
|
2.58491
|
|
CYCS
|
cytochrome c, somatic
|
2.48758
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.47329
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
2.4158
|
|
FCHO1
|
FCH domain only 1
|
2.39464
|
|
HOXA10
|
homeobox A10
|
2.34101
|
|
MTPAP
|
mitochondrial poly(A) polymerase
|
2.17715
|
|
IFT88
|
intraflagellar transport 88
|
2.13813
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.111
|
|
TERT
|
telomerase reverse transcriptase
|
2.09509
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
2.06299
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.03389
|
|
ZBTB18
|
zinc finger and BTB domain containing 18
|
2.03135
|
|
TRIM37
|
tripartite motif containing 37
|
2.00638
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-9.59356
|
|
LDHD
|
lactate dehydrogenase D
|
-6.87456
|
|
ADI1
|
acireductone dioxygenase 1
|
-6.25746
|
|
GNAS
|
GNAS complex locus
|
-5.40399
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-5.38271
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-4.38356
|
|
GOLT1B
|
golgi transport 1B
|
-3.91875
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-3.56653
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.41
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.22101
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.98291
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.88021
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.86661
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.85062
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.74218
|
|
ZNF586
|
zinc finger protein 586
|
-2.71375
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.45686
|
|
CCNC
|
cyclin C
|
-2.33644
|
|
NDEL1
|
nudE neurodevelopment protein 1-like 1
|
-2.29286
|
|
SNX11
|
sorting nexin 11
|
-2.27135
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.19598
|
|
CSK
|
c-src tyrosine kinase
|
-2.16075
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.13483
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.10748
|
|
GABRG2
|
gamma-aminobutyric acid (GABA) A receptor, gamma 2
|
-2.09356
|
|
LRRC47
|
leucine rich repeat containing 47
|
-2.06118
|
|
AOC3
|
amine oxidase, copper containing 3
|
-2.03243
|
|
RPS12
|
ribosomal protein S12
|
-2.0274
|
|
TAC1
|
tachykinin, precursor 1
|
-2.01075
|
|
SEC11A
|
SEC11 homolog A (S. cerevisiae)
|
-2.00485
|
