CRCGN014_HEPG2_3H:F15 Gene Set
Genes
37 genes differentially expressed following the CRCGN014_HEPG2_3H:F15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.77546
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.73351
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.53995
|
|
UBQLN2
|
ubiquilin 2
|
3.47608
|
|
STIMATE
|
STIM activating enhancer
|
3.41252
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.38178
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.34595
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.30184
|
|
CSK
|
c-src tyrosine kinase
|
3.11754
|
|
KIF14
|
kinesin family member 14
|
2.85169
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.33205
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.32355
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.29694
|
|
SLC25A14
|
solute carrier family 25 (mitochondrial carrier, brain), member 14
|
2.2858
|
|
CBR3
|
carbonyl reductase 3
|
2.28044
|
|
BMP4
|
bone morphogenetic protein 4
|
2.21802
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
2.0723
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.07008
|
|
GRB10
|
growth factor receptor-bound protein 10
|
2.0643
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.0216
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-9.89098
|
|
CCNB2
|
cyclin B2
|
-6.36968
|
|
GNAS
|
GNAS complex locus
|
-4.7581
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.52342
|
|
CD320
|
CD320 molecule
|
-3.50985
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.50511
|
|
TBC1D31
|
TBC1 domain family, member 31
|
-3.49714
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.20924
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.86044
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.83894
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.81344
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.57714
|
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
-2.54642
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.50598
|
|
ACR
|
acrosin
|
-2.30208
|
|
TSKU
|
tsukushi, small leucine rich proteoglycan
|
-2.23102
|
|
HMOX1
|
heme oxygenase 1
|
-2.22359
|