CRCGN014_HEPG2_3H:F16 Gene Set
Genes
35 genes differentially expressed following the CRCGN014_HEPG2_3H:F16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
5.67617
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
3.63061
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
3.57981
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.55964
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
3.17952
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.00138
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.00066
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.85884
|
|
STXBP2
|
syntaxin binding protein 2
|
2.67573
|
|
STIMATE
|
STIM activating enhancer
|
2.66994
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.50842
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.50233
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.27743
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.19134
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.15072
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.14838
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.08101
|
|
ZNF589
|
zinc finger protein 589
|
2.05806
|
|
PTK2
|
protein tyrosine kinase 2
|
2.02362
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.4778
|
|
LAP3
|
leucine aminopeptidase 3
|
-3.40812
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.40497
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.38029
|
|
LDHD
|
lactate dehydrogenase D
|
-3.21893
|
|
DSG2
|
desmoglein 2
|
-3.12618
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.08893
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.03236
|
|
CDC20
|
cell division cycle 20
|
-2.88352
|
|
CCNB2
|
cyclin B2
|
-2.86943
|
|
CSK
|
c-src tyrosine kinase
|
-2.62374
|
|
GNAS
|
GNAS complex locus
|
-2.58787
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.49301
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.44713
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.18449
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.14387
|
