CRCGN014_HEPG2_3H:F18 Gene Set
Genes
41 genes differentially expressed following the CRCGN014_HEPG2_3H:F18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAMLD1
|
mastermind-like domain containing 1
|
4.12258
|
|
MYLK
|
myosin light chain kinase
|
3.79826
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.35411
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.15988
|
|
PMM2
|
phosphomannomutase 2
|
3.07879
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
3.05868
|
|
IDE
|
insulin-degrading enzyme
|
2.98429
|
|
KIFBP
|
kinesin family binding protein
|
2.95086
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
2.93352
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.84647
|
|
UBQLN2
|
ubiquilin 2
|
2.81574
|
|
CSK
|
c-src tyrosine kinase
|
2.76304
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.72087
|
|
MAP7
|
microtubule-associated protein 7
|
2.51231
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.48455
|
|
ZBTB18
|
zinc finger and BTB domain containing 18
|
2.36916
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.23512
|
|
CYCS
|
cytochrome c, somatic
|
2.231
|
|
MOK
|
MOK protein kinase
|
2.18575
|
|
SGCB
|
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
|
2.01311
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.00283
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.26228
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.26866
|
|
COG7
|
component of oligomeric golgi complex 7
|
-3.52141
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.36037
|
|
VAT1
|
vesicle amine transport 1
|
-3.32946
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.05664
|
|
TLR4
|
toll-like receptor 4
|
-3.05118
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.85633
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.78484
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.7374
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.66944
|
|
GNAS
|
GNAS complex locus
|
-2.57343
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.47029
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.32145
|
|
CCNH
|
cyclin H
|
-2.25714
|
|
PPP2R5A
|
protein phosphatase 2, regulatory subunit B', alpha
|
-2.09381
|
|
CORO2A
|
coronin, actin binding protein, 2A
|
-2.05187
|
|
POLR2K
|
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
|
-2.03924
|
|
COX6C
|
cytochrome c oxidase subunit VIc
|
-2.02149
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.02014
|
