CRCGN014_HEPG2_3H:F19 Gene Set
Genes
52 genes differentially expressed following the CRCGN014_HEPG2_3H:F19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
7.10869
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.92701
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
6.45128
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.26355
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
4.45902
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.22289
|
|
E2F2
|
E2F transcription factor 2
|
3.62131
|
|
STIMATE
|
STIM activating enhancer
|
3.52035
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.2703
|
|
NOTCH1
|
notch 1
|
3.11898
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.10858
|
|
CSK
|
c-src tyrosine kinase
|
2.94754
|
|
HOXA10
|
homeobox A10
|
2.90561
|
|
GPATCH8
|
G patch domain containing 8
|
2.8558
|
|
MAP7
|
microtubule-associated protein 7
|
2.46175
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.43894
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.41821
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
2.3647
|
|
CYCS
|
cytochrome c, somatic
|
2.29207
|
|
RAP1GAP
|
RAP1 GTPase activating protein
|
2.2584
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.15395
|
|
ANO10
|
anoctamin 10
|
2.1458
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.11832
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
2.08839
|
|
EGF
|
epidermal growth factor
|
2.0784
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.02875
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-7.21701
|
|
PCNA
|
proliferating cell nuclear antigen
|
-7.0198
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.33138
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.63757
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.6309
|
|
TLR4
|
toll-like receptor 4
|
-3.37152
|
|
CD320
|
CD320 molecule
|
-3.3268
|
|
LDHD
|
lactate dehydrogenase D
|
-3.2443
|
|
CCNB2
|
cyclin B2
|
-3.17142
|
|
VAT1
|
vesicle amine transport 1
|
-2.902
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.87339
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.83898
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.73649
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.56998
|
|
RAI14
|
retinoic acid induced 14
|
-2.5229
|
|
GNAS
|
GNAS complex locus
|
-2.50262
|
|
TBC1D31
|
TBC1 domain family, member 31
|
-2.47116
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.37188
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-2.36322
|
|
CAAP1
|
caspase activity and apoptosis inhibitor 1
|
-2.21985
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.10355
|
|
ZNF586
|
zinc finger protein 586
|
-2.09813
|
|
ANKFY1
|
ankyrin repeat and FYVE domain containing 1
|
-2.05497
|
|
WDR70
|
WD repeat domain 70
|
-2.05154
|
|
PSKH1
|
protein serine kinase H1
|
-2.03342
|
|
FPR3
|
formyl peptide receptor 3
|
-2.01986
|
