CRCGN014_HEPG2_3H:F20 Gene Set
Genes
55 genes differentially expressed following the CRCGN014_HEPG2_3H:F20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
7.57786
|
|
UBQLN2
|
ubiquilin 2
|
6.13766
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.45882
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.93536
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.88872
|
|
SNX7
|
sorting nexin 7
|
3.8505
|
|
EPHB2
|
EPH receptor B2
|
3.705
|
|
NOTCH1
|
notch 1
|
3.24393
|
|
LCN2
|
lipocalin 2
|
2.99186
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.87492
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.80856
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.71509
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.48864
|
|
PTK2
|
protein tyrosine kinase 2
|
2.39194
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.38115
|
|
TUBGCP5
|
tubulin, gamma complex associated protein 5
|
2.37388
|
|
HOXA10
|
homeobox A10
|
2.34519
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.23805
|
|
HPCA
|
hippocalcin
|
2.16668
|
|
KIF14
|
kinesin family member 14
|
2.12037
|
|
GPATCH8
|
G patch domain containing 8
|
2.09386
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.08714
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.0647
|
|
TNP1
|
transition protein 1 (during histone to protamine replacement)
|
2.05747
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.04136
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.02723
|
|
DSN1
|
DSN1, MIS12 kinetochore complex component
|
2.00367
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
FASTKD5
|
FAST kinase domains 5
|
-4.44735
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.94858
|
|
MYC
|
v-myc avian myelocytomatosis viral oncogene homolog
|
-3.88317
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.8299
|
|
IER3
|
immediate early response 3
|
-3.81081
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.75936
|
|
ZNF586
|
zinc finger protein 586
|
-3.11811
|
|
CCNB1
|
cyclin B1
|
-3.00992
|
|
DNM1L
|
dynamin 1-like
|
-2.99852
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.93312
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.92982
|
|
BDH1
|
3-hydroxybutyrate dehydrogenase, type 1
|
-2.76839
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.74078
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.65272
|
|
CDC20
|
cell division cycle 20
|
-2.64985
|
|
LDHD
|
lactate dehydrogenase D
|
-2.63228
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.46845
|
|
GNAS
|
GNAS complex locus
|
-2.44319
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.28441
|
|
SNX11
|
sorting nexin 11
|
-2.28387
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.25697
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.14335
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.13973
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.1217
|
|
HMOX1
|
heme oxygenase 1
|
-2.11247
|
|
EGFL6
|
EGF-like-domain, multiple 6
|
-2.10971
|
|
HOXC5
|
homeobox C5
|
-2.09565
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.01805
|
