CRCGN014_HEPG2_3H:G04 Gene Set
Genes
43 genes differentially expressed following the CRCGN014_HEPG2_3H:G04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
4.69115
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.30938
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.17612
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
3.65383
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
3.636
|
|
HPRT1
|
hypoxanthine phosphoribosyltransferase 1
|
3.47714
|
|
IDE
|
insulin-degrading enzyme
|
3.37068
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.27864
|
|
UBQLN2
|
ubiquilin 2
|
3.10205
|
|
UBR7
|
ubiquitin protein ligase E3 component n-recognin 7 (putative)
|
3.09458
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.60316
|
|
KIF14
|
kinesin family member 14
|
2.59709
|
|
NOTCH1
|
notch 1
|
2.53686
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.47559
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.41227
|
|
SCCPDH
|
saccharopine dehydrogenase (putative)
|
2.31891
|
|
JADE2
|
jade family PHD finger 2
|
2.26699
|
|
FGF16
|
fibroblast growth factor 16
|
2.26403
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.18211
|
|
ZNF550
|
zinc finger protein 550
|
2.06737
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.06484
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.05245
|
|
SMIM41
|
small integral membrane protein 41
|
2.01893
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.00953
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.77481
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-4.65258
|
|
CCNB2
|
cyclin B2
|
-4.44064
|
|
LDHD
|
lactate dehydrogenase D
|
-4.25276
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-3.8994
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.39927
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.181
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.05838
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.76113
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.72269
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.53527
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.50822
|
|
WASHC4
|
WASH complex subunit 4
|
-2.3975
|
|
HMOX1
|
heme oxygenase 1
|
-2.38145
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-2.25302
|
|
ANKRD46
|
ankyrin repeat domain 46
|
-2.18667
|
|
CSK
|
c-src tyrosine kinase
|
-2.10329
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.04491
|
|
TSKU
|
tsukushi, small leucine rich proteoglycan
|
-2.01513
|
