| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methoxychlor 40.0 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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69 genes differentially expressed following the CRCGN014_HEPG2_3H:G05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDIT4 | DNA-damage-inducible transcript 4 | 10.0 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 7.28195 |
| ADRB2 | adrenoceptor beta 2, surface | 6.44648 |
| EGR1 | early growth response 1 | 6.23538 |
| IER3 | immediate early response 3 | 4.84435 |
| SHB | Src homology 2 domain containing adaptor protein B | 4.28631 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 4.23938 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.22021 |
| TRIB3 | tribbles pseudokinase 3 | 3.76589 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.59218 |
| TRIB1 | tribbles pseudokinase 1 | 3.57719 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.29981 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 2.99239 |
| HYOU1 | hypoxia up-regulated 1 | 2.91838 |
| EPN2 | epsin 2 | 2.90072 |
| FOSL1 | FOS-like antigen 1 | 2.86531 |
| HOXA10 | homeobox A10 | 2.80745 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.75451 |
| SCRN1 | secernin 1 | 2.63084 |
| PFKL | phosphofructokinase, liver | 2.62095 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.56719 |
| MAP7 | microtubule-associated protein 7 | 2.38606 |
| CHN1 | chimerin 1 | 2.38605 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.36836 |
| DIPK1A | divergent protein kinase domain 1A | 2.36316 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.34216 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 2.31454 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 2.23731 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.23441 |
| CDK19 | cyclin-dependent kinase 19 | 2.18222 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 2.14781 |
| ZFP36 | ZFP36 ring finger protein | 2.12443 |
| ICAM1 | intercellular adhesion molecule 1 | 2.12009 |
| NOSIP | nitric oxide synthase interacting protein | 2.11674 |
| ABHD11 | abhydrolase domain containing 11 | 2.10137 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 2.08968 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FASTKD5 | FAST kinase domains 5 | -7.64855 |
| CDC20 | cell division cycle 20 | -4.84085 |
| TSPAN4 | tetraspanin 4 | -3.94756 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.91303 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.86394 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -3.83531 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.829 |
| ZNF586 | zinc finger protein 586 | -3.55035 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.43743 |
| CDK1 | cyclin-dependent kinase 1 | -3.37878 |
| VAT1 | vesicle amine transport 1 | -3.34598 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.31166 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.25565 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.01499 |
| GNAS | GNAS complex locus | -2.97467 |
| TXNDC9 | thioredoxin domain containing 9 | -2.77666 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -2.63582 |
| LDHD | lactate dehydrogenase D | -2.56563 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.54438 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -2.47408 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.39036 |
| EED | embryonic ectoderm development | -2.34173 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -2.30598 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -2.23875 |
| FOXO4 | forkhead box O4 | -2.22418 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -2.22309 |
| PARP2 | poly (ADP-ribose) polymerase 2 | -2.21781 |
| EGF | epidermal growth factor | -2.14891 |
| CDC25B | cell division cycle 25B | -2.14023 |
| ANKRD10 | ankyrin repeat domain 10 | -2.06954 |
| THAP12 | THAP domain containing 12 | -2.04756 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.04506 |
| BLCAP | bladder cancer associated protein | -2.02397 |
