CRCGN014_HEPG2_3H:G06 Gene Set
Genes
38 genes differentially expressed following the CRCGN014_HEPG2_3H:G06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
KIF14
|
kinesin family member 14
|
4.41662
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.39528
|
|
MYLK
|
myosin light chain kinase
|
3.89773
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.66547
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.46618
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.2079
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.02745
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.88565
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.7057
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.54925
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.53834
|
|
CCNF
|
cyclin F
|
2.338
|
|
GPATCH8
|
G patch domain containing 8
|
2.28935
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.26973
|
|
RRAGA
|
Ras-related GTP binding A
|
2.21936
|
|
KIF20A
|
kinesin family member 20A
|
2.15318
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.01621
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-6.9722
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.2874
|
|
SNX11
|
sorting nexin 11
|
-3.82344
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.69661
|
|
HAT1
|
histone acetyltransferase 1
|
-3.53906
|
|
BLCAP
|
bladder cancer associated protein
|
-3.52086
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.51699
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.18984
|
|
LDHD
|
lactate dehydrogenase D
|
-3.18038
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.04035
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
-2.98691
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.86374
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.74924
|
|
ZNF586
|
zinc finger protein 586
|
-2.71363
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.70439
|
|
CSK
|
c-src tyrosine kinase
|
-2.57302
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.42958
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.42665
|
|
HMOX1
|
heme oxygenase 1
|
-2.39506
|
|
CCNB1
|
cyclin B1
|
-2.21046
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.02463
|