CRCGN014_HEPG2_3H:G07 Gene Set
Genes
43 genes differentially expressed following the CRCGN014_HEPG2_3H:G07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
7.13421
|
|
STIMATE
|
STIM activating enhancer
|
5.99428
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
5.11875
|
|
CBR3
|
carbonyl reductase 3
|
4.34387
|
|
MAP7
|
microtubule-associated protein 7
|
3.848
|
|
ILK
|
integrin-linked kinase
|
2.9517
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.9312
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.87481
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.81833
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.81562
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.73063
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.72287
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.65389
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.53634
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.37724
|
|
CHEK2
|
checkpoint kinase 2
|
2.35278
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.35088
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.2602
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.03493
|
|
SNX7
|
sorting nexin 7
|
2.01373
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-7.06739
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.49163
|
|
LDHD
|
lactate dehydrogenase D
|
-4.40184
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.81103
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.67155
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.47617
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.42698
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.29016
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.22113
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.91652
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.77127
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.75508
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.62144
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.55465
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.37395
|
|
SPAG4
|
sperm associated antigen 4
|
-2.32691
|
|
APIP
|
APAF1 interacting protein
|
-2.3021
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.28842
|
|
S100G
|
S100 calcium binding protein G
|
-2.24698
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.10951
|
|
ZNF586
|
zinc finger protein 586
|
-2.04067
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.03958
|
|
GUCY2F
|
guanylate cyclase 2F, retinal
|
-2.00842
|
