CRCGN014_HEPG2_3H:G11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (2s)-2-amino-4-(ethylsulfanyl)butanoic acid 21.44 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN014_HEPG2_3H:G11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TIAM1 T-cell lymphoma invasion and metastasis 1 5.36916
LCN2 lipocalin 2 4.8751
BACE2 beta-site APP-cleaving enzyme 2 4.71999
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.51796
PEX11A peroxisomal biogenesis factor 11 alpha 4.14488
CCP110 centriolar coiled coil protein 110kDa 3.57736
PPARG peroxisome proliferator-activated receptor gamma 3.23338
AMDHD2 amidohydrolase domain containing 2 3.08624
CTTN cortactin 3.02076
TEX10 testis expressed 10 2.87548
DYNLT3 dynein, light chain, Tctex-type 3 2.71483
GPATCH8 G patch domain containing 8 2.56024
HPRT1 hypoxanthine phosphoribosyltransferase 1 2.4411
AXIN1 axin 1 2.19474
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 2.11502
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 2.03695

decreased expression

Symbol Name Standardized Value
TLR4 toll-like receptor 4 -6.69836
GNAS GNAS complex locus -5.99695
FGFR4 fibroblast growth factor receptor 4 -4.12573
GOLT1B golgi transport 1B -3.37466
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -3.11307
THAP11 THAP domain containing 11 -2.87705
ZNF586 zinc finger protein 586 -2.70888
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.67083
LPA lipoprotein, Lp(a) -2.64633
GYS2 glycogen synthase 2 (liver) -2.24323
RECQL RecQ helicase-like -2.22698
GPR22 G protein-coupled receptor 22 -2.21114
NTSR2 neurotensin receptor 2 -2.19411
SNX11 sorting nexin 11 -2.13141
FNDC3B fibronectin type III domain containing 3B -2.11657
EIF5 eukaryotic translation initiation factor 5 -2.11155
CRHBP corticotropin releasing hormone binding protein -2.11136
CSNK1E casein kinase 1, epsilon -2.10142
TMOD2 tropomodulin 2 (neuronal) -2.0897
CEP72 centrosomal protein 72kDa -2.01472