CRCGN014_HEPG2_3H:G14 Gene Set
Genes
49 genes differentially expressed following the CRCGN014_HEPG2_3H:G14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.41223
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.03238
|
|
CCDC92
|
coiled-coil domain containing 92
|
3.77417
|
|
MSRA
|
methionine sulfoxide reductase A
|
3.75804
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.72624
|
|
CCNF
|
cyclin F
|
3.69312
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.64195
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.58219
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.34905
|
|
CBR3
|
carbonyl reductase 3
|
3.27001
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.2465
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.23125
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.96433
|
|
GATA3
|
GATA binding protein 3
|
2.93745
|
|
UBQLN2
|
ubiquilin 2
|
2.83562
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.7613
|
|
HPRT1
|
hypoxanthine phosphoribosyltransferase 1
|
2.68853
|
|
CHN1
|
chimerin 1
|
2.4494
|
|
DHDDS
|
dehydrodolichyl diphosphate synthase
|
2.44822
|
|
PRR15L
|
proline rich 15-like
|
2.44656
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.41685
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.40711
|
|
BORA
|
bora, aurora kinase A activator
|
2.37091
|
|
SORBS3
|
sorbin and SH3 domain containing 3
|
2.35819
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.25975
|
|
SAA2
|
serum amyloid A2
|
2.14323
|
|
RANBP6
|
RAN binding protein 6
|
2.13309
|
|
SLC25A14
|
solute carrier family 25 (mitochondrial carrier, brain), member 14
|
2.0627
|
|
GALE
|
UDP-galactose-4-epimerase
|
2.01337
|
|
PFAS
|
phosphoribosylformylglycinamidine synthase
|
2.00449
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-8.85791
|
|
CDC20
|
cell division cycle 20
|
-6.543
|
|
LDHD
|
lactate dehydrogenase D
|
-6.43092
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.39479
|
|
TRIB3
|
tribbles pseudokinase 3
|
-5.31677
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.50313
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.43185
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.2336
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.87627
|
|
CLTB
|
clathrin, light chain B
|
-2.8336
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.82856
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-2.78918
|
|
TLR4
|
toll-like receptor 4
|
-2.60762
|
|
CCNH
|
cyclin H
|
-2.28814
|
|
CCNB2
|
cyclin B2
|
-2.1737
|
|
EDN1
|
endothelin 1
|
-2.13941
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.13444
|
|
TBX2
|
T-box 2
|
-2.13407
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.08882
|