CRCGN014_HEPG2_3H:G14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description quinapril 21.47 um perturbation at 3 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

49 genes differentially expressed following the CRCGN014_HEPG2_3H:G14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.41223
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 4.03238
CCDC92 coiled-coil domain containing 92 3.77417
MSRA methionine sulfoxide reductase A 3.75804
CARMIL1 capping protein regulator and myosin 1 linker 1 3.72624
CCNF cyclin F 3.69312
CIAO3 cytosolic iron-sulfur assembly component 3 3.64195
GSTZ1 glutathione S-transferase zeta 1 3.58219
PEX11A peroxisomal biogenesis factor 11 alpha 3.34905
CBR3 carbonyl reductase 3 3.27001
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.2465
CHMP6 charged multivesicular body protein 6 3.23125
CXCL2 chemokine (C-X-C motif) ligand 2 2.96433
GATA3 GATA binding protein 3 2.93745
UBQLN2 ubiquilin 2 2.83562
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.7613
HPRT1 hypoxanthine phosphoribosyltransferase 1 2.68853
CHN1 chimerin 1 2.4494
DHDDS dehydrodolichyl diphosphate synthase 2.44822
PRR15L proline rich 15-like 2.44656
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.41685
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.40711
BORA bora, aurora kinase A activator 2.37091
SORBS3 sorbin and SH3 domain containing 3 2.35819
NOSIP nitric oxide synthase interacting protein 2.25975
SAA2 serum amyloid A2 2.14323
RANBP6 RAN binding protein 6 2.13309
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.0627
GALE UDP-galactose-4-epimerase 2.01337
PFAS phosphoribosylformylglycinamidine synthase 2.00449

decreased expression

Symbol Name Standardized Value
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -8.85791
CDC20 cell division cycle 20 -6.543
LDHD lactate dehydrogenase D -6.43092
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -6.39479
TRIB3 tribbles pseudokinase 3 -5.31677
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.50313
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.43185
MAPK13 mitogen-activated protein kinase 13 -3.2336
PCNA proliferating cell nuclear antigen -2.87627
CLTB clathrin, light chain B -2.8336
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.82856
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -2.78918
TLR4 toll-like receptor 4 -2.60762
CCNH cyclin H -2.28814
CCNB2 cyclin B2 -2.1737
EDN1 endothelin 1 -2.13941
ACAA1 acetyl-CoA acyltransferase 1 -2.13444
TBX2 T-box 2 -2.13407
ANKRD10 ankyrin repeat domain 10 -2.08882