CRCGN014_HEPG2_3H:G16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description triamcinolone 20.09 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

52 genes differentially expressed following the CRCGN014_HEPG2_3H:G16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 6.98996
GPATCH8 G patch domain containing 8 5.33478
UBQLN2 ubiquilin 2 5.2983
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.29015
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 4.16066
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.04067
KIFBP kinesin family binding protein 3.86782
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.78596
CEP57 centrosomal protein 57kDa 3.74854
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.72442
GSTZ1 glutathione S-transferase zeta 1 3.69947
PPARG peroxisome proliferator-activated receptor gamma 3.5338
HOXA10 homeobox A10 3.49519
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 3.33577
CCP110 centriolar coiled coil protein 110kDa 3.01862
CHMP6 charged multivesicular body protein 6 2.86811
PLSCR3 phospholipid scramblase 3 2.5993
SAA2 serum amyloid A2 2.54622
HSPA1A heat shock 70kDa protein 1A 2.43609
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.33274
BORA bora, aurora kinase A activator 2.25561
UFM1 ubiquitin-fold modifier 1 2.14898
KIF14 kinesin family member 14 2.09628
MAK16 MAK16 homolog (S. cerevisiae) 2.06389
LOC102724560 cystathionine beta-synthase 2.02948

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -8.92445
ZNF586 zinc finger protein 586 -5.43856
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -5.02227
NT5DC2 5'-nucleotidase domain containing 2 -4.71058
KDM3A lysine (K)-specific demethylase 3A -4.57851
PCNA proliferating cell nuclear antigen -4.41075
RPS4Y1 ribosomal protein S4, Y-linked 1 -4.02438
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -3.18972
YME1L1 YME1-like 1 ATPase -3.02558
TLCD3A TLC domain containing 3A -2.94222
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.93154
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.7628
ERC2 ELKS/RAB6-interacting/CAST family member 2 -2.71707
PRPF4 pre-mRNA processing factor 4 -2.34184
PLSCR2 phospholipid scramblase 2 -2.29634
OXA1L oxidase (cytochrome c) assembly 1-like -2.25689
SHCBP1L SHC SH2-domain binding protein 1-like -2.23497
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -2.21919
ZW10 zw10 kinetochore protein -2.18237
KLK14 kallikrein-related peptidase 14 -2.17573
KIFC3 kinesin family member C3 -2.14067
DIXDC1 DIX domain containing 1 -2.11193
EGF epidermal growth factor -2.07847
SH3BP1 SH3-domain binding protein 1 -2.05299
AKAP3 A kinase (PRKA) anchor protein 3 -2.04173
SPATA6 spermatogenesis associated 6 -2.02924
CCIN calicin -2.01317