CRCGN014_HEPG2_3H:G17 Gene Set
Genes
46 genes differentially expressed following the CRCGN014_HEPG2_3H:G17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TATDN2
|
TatD DNase domain containing 2
|
3.80703
|
|
MYLK
|
myosin light chain kinase
|
3.59645
|
|
STIMATE
|
STIM activating enhancer
|
3.24021
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.18222
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.13187
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.07432
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.07045
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.02743
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.91077
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.80328
|
|
PRKCH
|
protein kinase C, eta
|
2.72616
|
|
HOXA10
|
homeobox A10
|
2.70799
|
|
WASF3
|
WAS protein family, member 3
|
2.69009
|
|
KIF20A
|
kinesin family member 20A
|
2.50967
|
|
PTDSS1
|
phosphatidylserine synthase 1
|
2.47525
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.46565
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.32945
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.2844
|
|
CYCS
|
cytochrome c, somatic
|
2.24901
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.24195
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.1436
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-7.25139
|
|
PCNA
|
proliferating cell nuclear antigen
|
-6.44018
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.41533
|
|
ENOPH1
|
enolase-phosphatase 1
|
-3.54636
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-3.44785
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.30086
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.25946
|
|
LDHD
|
lactate dehydrogenase D
|
-3.15993
|
|
CDC20
|
cell division cycle 20
|
-3.15809
|
|
GOLT1B
|
golgi transport 1B
|
-3.13483
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.06683
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-3.06089
|
|
TLR4
|
toll-like receptor 4
|
-3.0575
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.01922
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.90584
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.84215
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-2.81046
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.79368
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.79133
|
|
WASHC4
|
WASH complex subunit 4
|
-2.55488
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.52823
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.37018
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.32944
|
|
RAI14
|
retinoic acid induced 14
|
-2.13626
|
|
GNAS
|
GNAS complex locus
|
-2.07498
|
