CRCGN014_HEPG2_3H:G18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acetohexamide 20.96 um perturbation at 3 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

46 genes differentially expressed following the CRCGN014_HEPG2_3H:G18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCL2 chemokine (C-C motif) ligand 2 5.97489
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.58709
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.93414
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.68371
EPHB2 EPH receptor B2 3.65225
DYNLT3 dynein, light chain, Tctex-type 3 3.59533
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.56101
AMDHD2 amidohydrolase domain containing 2 3.24814
PLSCR3 phospholipid scramblase 3 3.125
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.0401
CXCL2 chemokine (C-X-C motif) ligand 2 3.03982
BZW2 basic leucine zipper and W2 domains 2 2.90128
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.86399
HOXA10 homeobox A10 2.67834
TREM1 triggering receptor expressed on myeloid cells 1 2.66458
CRTAP cartilage associated protein 2.65691
ATP11B ATPase, class VI, type 11B 2.60164
STXBP2 syntaxin binding protein 2 2.4408
ZNF589 zinc finger protein 589 2.38924
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.38242
STIMATE STIM activating enhancer 2.27203
LOC122526780 uncharacterized LOC122526780 2.07107
PLCG1 phospholipase C, gamma 1 2.05215
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 2.0092

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -6.23317
PCNA proliferating cell nuclear antigen -5.97839
ZNF586 zinc finger protein 586 -5.22525
CCDC86 coiled-coil domain containing 86 -3.81599
COG2 component of oligomeric golgi complex 2 -3.74916
C2CD5 C2 calcium-dependent domain containing 5 -3.59136
FAIM Fas apoptotic inhibitory molecule -3.33665
CD320 CD320 molecule -3.15861
PCCB propionyl CoA carboxylase, beta polypeptide -3.0986
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.02909
RPS4Y1 ribosomal protein S4, Y-linked 1 -2.89059
DERA deoxyribose-phosphate aldolase (putative) -2.88736
TRIB3 tribbles pseudokinase 3 -2.8521
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.74464
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.70704
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.52153
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.42381
VAT1 vesicle amine transport 1 -2.39735
LOC124907782 dual specificity protein phosphatase 22 -2.36635
NGRN neugrin, neurite outgrowth associated -2.15507
NUSAP1 nucleolar and spindle associated protein 1 -2.12974
ACLY ATP citrate lyase -2.0174