CRCGN014_HEPG2_3H:G20 Gene Set
Genes
56 genes differentially expressed following the CRCGN014_HEPG2_3H:G20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GPATCH8
|
G patch domain containing 8
|
5.4544
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.79703
|
|
LCN2
|
lipocalin 2
|
4.4789
|
|
TXNRD1
|
thioredoxin reductase 1
|
4.25721
|
|
CSK
|
c-src tyrosine kinase
|
3.79378
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.71931
|
|
FOSL1
|
FOS-like antigen 1
|
3.44776
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.37704
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.2426
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.98912
|
|
HMOX1
|
heme oxygenase 1
|
2.79079
|
|
KLHL21
|
kelch-like family member 21
|
2.49405
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.42995
|
|
IER3
|
immediate early response 3
|
2.40709
|
|
RRAGA
|
Ras-related GTP binding A
|
2.36085
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.32063
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.29612
|
|
TRIB1
|
tribbles pseudokinase 1
|
2.26099
|
|
HOXA10
|
homeobox A10
|
2.24172
|
|
CYCS
|
cytochrome c, somatic
|
2.23385
|
|
RAP1GAP
|
RAP1 GTPase activating protein
|
2.19326
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.18447
|
|
MAP7
|
microtubule-associated protein 7
|
2.14753
|
|
TRIM16
|
tripartite motif containing 16
|
2.13491
|
|
USP6NL
|
USP6 N-terminal like
|
2.13365
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
2.13075
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.11813
|
|
SQSTM1
|
sequestosome 1
|
2.06648
|
|
ILK
|
integrin-linked kinase
|
2.0572
|
|
EVL
|
Enah/Vasp-like
|
2.02812
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.65053
|
|
ZNF586
|
zinc finger protein 586
|
-5.5196
|
|
SPAG4
|
sperm associated antigen 4
|
-4.30256
|
|
PEG10
|
paternally expressed 10
|
-4.22999
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.01461
|
|
CDC20
|
cell division cycle 20
|
-3.97563
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.62598
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.55697
|
|
LDHD
|
lactate dehydrogenase D
|
-3.43566
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.41037
|
|
CCNB1
|
cyclin B1
|
-3.1492
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.07605
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.96754
|
|
CD320
|
CD320 molecule
|
-2.89652
|
|
CCNB2
|
cyclin B2
|
-2.89038
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.87412
|
|
MVP
|
major vault protein
|
-2.59427
|
|
WASHC4
|
WASH complex subunit 4
|
-2.51817
|
|
TBC1D31
|
TBC1 domain family, member 31
|
-2.4295
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-2.25709
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.22513
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.19292
|
|
MAD2L1
|
MAD2 mitotic arrest deficient-like 1 (yeast)
|
-2.17389
|
|
EFNB2
|
ephrin-B2
|
-2.0961
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-2.07593
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.02802
|
