CRCGN014_HEPG2_3H:G21 Gene Set
Genes
44 genes differentially expressed following the CRCGN014_HEPG2_3H:G21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
5.42594
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
5.30245
|
|
E2F2
|
E2F transcription factor 2
|
5.17143
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
5.15313
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.507
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.33021
|
|
CYCS
|
cytochrome c, somatic
|
4.05204
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.88346
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.658
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.53668
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.28299
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.18469
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.17461
|
|
VGLL4
|
vestigial-like family member 4
|
3.16066
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.03845
|
|
PRKCH
|
protein kinase C, eta
|
2.91965
|
|
CSK
|
c-src tyrosine kinase
|
2.87822
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.86333
|
|
CHEK2
|
checkpoint kinase 2
|
2.86321
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.74049
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.72201
|
|
NDUFA3
|
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
|
2.57685
|
|
KIF14
|
kinesin family member 14
|
2.2987
|
|
LYRM9
|
LYR motif containing 9
|
2.14235
|
|
MEST
|
mesoderm specific transcript
|
2.1142
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.11167
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.68561
|
|
VAT1
|
vesicle amine transport 1
|
-5.39374
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.25376
|
|
CCNB2
|
cyclin B2
|
-4.10884
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.01748
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.00723
|
|
CD320
|
CD320 molecule
|
-3.97621
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.81716
|
|
ZNF586
|
zinc finger protein 586
|
-3.79622
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.51038
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.2099
|
|
HMOX1
|
heme oxygenase 1
|
-2.9008
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.78828
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.69481
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.63924
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
-2.14152
|
|
ALKBH1
|
alkB, alkylation repair homolog 1 (E. coli)
|
-2.11997
|
|
SNX11
|
sorting nexin 11
|
-2.08022
|
