| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | edaravone 40.2 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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60 genes differentially expressed following the CRCGN014_HEPG2_3H:G22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 8.04053 |
| CYCS | cytochrome c, somatic | 7.40337 |
| E2F2 | E2F transcription factor 2 | 5.11697 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.72172 |
| SKIC8 | SKI8 subunit of superkiller complex | 4.68944 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.4328 |
| BZW2 | basic leucine zipper and W2 domains 2 | 3.04083 |
| RPL39L | ribosomal protein L39-like | 2.94106 |
| PFKL | phosphofructokinase, liver | 2.90127 |
| GSK3B | glycogen synthase kinase 3 beta | 2.85842 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.77617 |
| CCNA1 | cyclin A1 | 2.75978 |
| MEST | mesoderm specific transcript | 2.73259 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.52309 |
| RAP1GAP | RAP1 GTPase activating protein | 2.47493 |
| SLC25A46 | solute carrier family 25, member 46 | 2.38089 |
| KIF20A | kinesin family member 20A | 2.37505 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.35752 |
| DIPK1A | divergent protein kinase domain 1A | 2.35447 |
| RRAGA | Ras-related GTP binding A | 2.29 |
| SF3B4 | splicing factor 3b, subunit 4, 49kDa | 2.25789 |
| CAMTA1 | calmodulin binding transcription activator 1 | 2.21313 |
| CCDC86 | coiled-coil domain containing 86 | 2.21019 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) | 2.20565 |
| DHRS4 | dehydrogenase/reductase (SDR family) member 4 | 2.2005 |
| FOCAD | focadhesin | 2.10766 |
| MCM5 | minichromosome maintenance complex component 5 | 2.09396 |
| DNM2 | dynamin 2 | 2.08732 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.06764 |
| CA9 | carbonic anhydrase IX | 2.06636 |
| BCAS3 | breast carcinoma amplified sequence 3 | 2.02659 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant | 2.02558 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| ZNF586 | zinc finger protein 586 | -7.31157 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.0725 |
| SLC35F2 | solute carrier family 35, member F2 | -3.87222 |
| THAP11 | THAP domain containing 11 | -3.80624 |
| CCNH | cyclin H | -3.75305 |
| DNM1L | dynamin 1-like | -3.70885 |
| RHEB | Ras homolog enriched in brain | -3.62021 |
| TXNDC9 | thioredoxin domain containing 9 | -3.57352 |
| GNAS | GNAS complex locus | -3.25788 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -3.15525 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.08795 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.99343 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.85116 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -2.76318 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.73656 |
| WASHC4 | WASH complex subunit 4 | -2.66118 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.6007 |
| MRPL49 | mitochondrial ribosomal protein L49 | -2.52697 |
| PUS7 | pseudouridylate synthase 7 (putative) | -2.34301 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.27141 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -2.25959 |
| TMEM33 | transmembrane protein 33 | -2.19881 |
| CAB39 | calcium binding protein 39 | -2.14384 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -2.12499 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -2.02607 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 | -2.02322 |
| TSPAN4 | tetraspanin 4 | -2.02093 |
