| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hexachlorophene 40.0 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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96 genes differentially expressed following the CRCGN014_HEPG2_3H:G23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | 10.0 |
| EGR1 | early growth response 1 | 6.83775 |
| JUN | jun proto-oncogene | 6.3847 |
| BAG3 | BCL2-associated athanogene 3 | 5.85504 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 5.597 |
| HSPB1 | heat shock 27kDa protein 1 | 5.53826 |
| HSPA1B | heat shock 70kDa protein 1B | 4.9951 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 4.94484 |
| SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1 | 4.48943 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 3.83841 |
| UBQLN2 | ubiquilin 2 | 3.76265 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.76043 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 3.66218 |
| H2BC12 | H2B clustered histone 12 | 3.56552 |
| MEST | mesoderm specific transcript | 3.45035 |
| ATF3 | activating transcription factor 3 | 3.39845 |
| INTS3 | integrator complex subunit 3 | 3.34509 |
| STAP2 | signal transducing adaptor family member 2 | 3.33238 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.27667 |
| SFTPB | surfactant protein B | 3.27192 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.10995 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 3.10091 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 2.98337 |
| SATB1 | SATB homeobox 1 | 2.97402 |
| ZFP36 | ZFP36 ring finger protein | 2.97242 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.82061 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 2.73717 |
| INPP1 | inositol polyphosphate-1-phosphatase | 2.70313 |
| TRIB1 | tribbles pseudokinase 1 | 2.6918 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 2.62094 |
| IER5 | immediate early response 5 | 2.57775 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.53056 |
| RHOB | ras homolog family member B | 2.37743 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.37317 |
| CDC34 | cell division cycle 34 | 2.36879 |
| CRTAP | cartilage associated protein | 2.3452 |
| FOXO4 | forkhead box O4 | 2.34245 |
| ATG101 | autophagy related 101 | 2.33347 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 2.31021 |
| BZW2 | basic leucine zipper and W2 domains 2 | 2.23474 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 2.22855 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.21543 |
| LOC122526780 | uncharacterized LOC122526780 | 2.21531 |
| ANKRD10 | ankyrin repeat domain 10 | 2.19721 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.16492 |
| TSC22D1 | TSC22 domain family, member 1 | 2.15133 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 2.15023 |
| HINFP | histone H4 transcription factor | 2.14016 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 2.1146 |
| WWC2 | WW and C2 domain containing 2 | 2.04416 |
| KLF6 | Kruppel-like factor 6 | 2.01588 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.00708 |
| GATA2 | GATA binding protein 2 | 2.00328 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -6.84758 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.54579 |
| ZNF586 | zinc finger protein 586 | -5.70384 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.63693 |
| GNAS | GNAS complex locus | -5.09342 |
| CDC20 | cell division cycle 20 | -4.36287 |
| SLC35F2 | solute carrier family 35, member F2 | -4.32016 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -4.26879 |
| PCNA | proliferating cell nuclear antigen | -3.94677 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -3.50675 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.46179 |
| DNM1L | dynamin 1-like | -3.46171 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -3.36374 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | -3.3516 |
| PEG10 | paternally expressed 10 | -3.20651 |
| PROS1 | protein S (alpha) | -3.12683 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.94198 |
| CAB39 | calcium binding protein 39 | -2.78635 |
| MAT2A | methionine adenosyltransferase II, alpha | -2.77614 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -2.73665 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.69112 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -2.65312 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain | -2.51485 |
| TLCD3A | TLC domain containing 3A | -2.30655 |
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | -2.3043 |
| NUP85 | nucleoporin 85kDa | -2.28277 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -2.17846 |
| ERLIN2 | ER lipid raft associated 2 | -2.17377 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -2.14757 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.1465 |
| DEPDC5 | DEP domain containing 5 | -2.13185 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -2.12895 |
| MNMIP1 | manchette microtubule inner protein 1 | -2.11727 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 | -2.11474 |
| DDHD2 | DDHD domain containing 2 | -2.10731 |
| HRH2 | histamine receptor H2 | -2.09358 |
| IKZF3 | IKAROS family zinc finger 3 (Aiolos) | -2.085 |
| IGF2R | insulin-like growth factor 2 receptor | -2.077 |
| TXLNA | taxilin alpha | -2.05718 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 | -2.04332 |
| NAT10 | N-acetyltransferase 10 (GCN5-related) | -2.03271 |
| DCK | deoxycytidine kinase | -2.03031 |
| TMEM121 | transmembrane protein 121 | -2.02968 |
