CRCGN014_HEPG2_3H:G24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitrobenzene 41.2 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN014_HEPG2_3H:G24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 7.95651
TIAM1 T-cell lymphoma invasion and metastasis 1 3.17844
LOC122526780 uncharacterized LOC122526780 3.01201
CEMIP2 cell migration inducing hyaluronidase 2 2.94711
JADE2 jade family PHD finger 2 2.84807
ZNF589 zinc finger protein 589 2.84765
BMP4 bone morphogenetic protein 4 2.80649
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.77956
TRAPPC8 trafficking protein particle complex 8 2.53455
PCDHB11 protocadherin beta 11 2.53403
LPAR2 lysophosphatidic acid receptor 2 2.37217
ZBTB18 zinc finger and BTB domain containing 18 2.37213
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.3023
GSTZ1 glutathione S-transferase zeta 1 2.17048
PNKP polynucleotide kinase 3'-phosphatase 2.0996
PRR15L proline rich 15-like 2.05899
TTC17 tetratricopeptide repeat domain 17 2.03986
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.03698
STK25 serine/threonine kinase 25 2.03448
NUP133 nucleoporin 133kDa 2.03118

decreased expression

Symbol Name Standardized Value
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -7.92978
LDHD lactate dehydrogenase D -6.82011
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -6.28627
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.70734
CCNB2 cyclin B2 -4.58089
SLC35F2 solute carrier family 35, member F2 -3.63397
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -3.48943
RGS2 regulator of G-protein signaling 2 -2.46438
IL2RG interleukin 2 receptor, gamma -2.41565
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.27074
CLTB clathrin, light chain B -2.25041
TXNDC9 thioredoxin domain containing 9 -2.193
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.16829
BPHL biphenyl hydrolase-like (serine hydrolase) -2.1482
CD96 CD96 molecule -2.11672
DCK deoxycytidine kinase -2.03825
MYL9 myosin, light chain 9, regulatory -2.00336