CRCGN014_HEPG2_3H:H06 Gene Set
Genes
46 genes differentially expressed following the CRCGN014_HEPG2_3H:H06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHN1
|
chimerin 1
|
5.34451
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.96507
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
4.08488
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.95512
|
|
KIF14
|
kinesin family member 14
|
3.88664
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.3945
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.23794
|
|
E2F2
|
E2F transcription factor 2
|
3.0991
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.09557
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
3.06837
|
|
CCNA1
|
cyclin A1
|
2.95235
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.85994
|
|
STIMATE
|
STIM activating enhancer
|
2.61223
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.60061
|
|
EVL
|
Enah/Vasp-like
|
2.59855
|
|
ZBTB35
|
zinc finger and BTB domain containing 35
|
2.46427
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.26377
|
|
FKBP14
|
FK506 binding protein 14, 22 kDa
|
2.25528
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.20954
|
|
TBPL1
|
TBP-like 1
|
2.14966
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.11669
|
|
UBR7
|
ubiquitin protein ligase E3 component n-recognin 7 (putative)
|
2.1153
|
|
GATA3
|
GATA binding protein 3
|
2.11494
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-7.03177
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.22888
|
|
TLR4
|
toll-like receptor 4
|
-4.45844
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.39158
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.20938
|
|
CDC20
|
cell division cycle 20
|
-4.15811
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.04019
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.4292
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-3.04732
|
|
ZNF586
|
zinc finger protein 586
|
-2.97797
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.87034
|
|
VAT1
|
vesicle amine transport 1
|
-2.80705
|
|
COG2
|
component of oligomeric golgi complex 2
|
-2.70827
|
|
LDHD
|
lactate dehydrogenase D
|
-2.68382
|
|
TOMM70
|
translocase of outer mitochondrial membrane 70
|
-2.55996
|
|
PSMD10
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
|
-2.53896
|
|
RPIA
|
ribose 5-phosphate isomerase A
|
-2.5336
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.2756
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.26693
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.1102
|
|
ZNF552
|
zinc finger protein 552
|
-2.08844
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-2.05804
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-2.0437
|
