| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | UnTrt perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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64 genes differentially expressed following the CRCGN014_HEPG2_3H:H10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHN1 | chimerin 1 | 4.91499 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.73911 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 4.50654 |
| UBQLN2 | ubiquilin 2 | 4.40463 |
| NOSIP | nitric oxide synthase interacting protein | 4.30802 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.28884 |
| CHMP6 | charged multivesicular body protein 6 | 4.26605 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.96887 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 3.90605 |
| CYCS | cytochrome c, somatic | 3.78047 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.59744 |
| TEX10 | testis expressed 10 | 3.40033 |
| MOK | MOK protein kinase | 3.33934 |
| VGLL4 | vestigial-like family member 4 | 3.33914 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.32312 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 | 3.04157 |
| ABHD6 | abhydrolase domain containing 6 | 2.95159 |
| CORO1A | coronin, actin binding protein, 1A | 2.90725 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.79725 |
| RAB21 | RAB21, member RAS oncogene family | 2.7117 |
| TSPAN6 | tetraspanin 6 | 2.67043 |
| CCNF | cyclin F | 2.62779 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.55253 |
| LOC122526780 | uncharacterized LOC122526780 | 2.35404 |
| TCTA | T-cell leukemia translocation altered | 2.32189 |
| IFI44L | interferon-induced protein 44-like | 2.32099 |
| AXIN1 | axin 1 | 2.23075 |
| FHL2 | four and a half LIM domains 2 | 2.17953 |
| SALL2 | spalt-like transcription factor 2 | 2.1505 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.14289 |
| NR2E1 | nuclear receptor subfamily 2, group E, member 1 | 2.03754 |
| ANO10 | anoctamin 10 | 2.0037 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -7.35074 |
| FGFR4 | fibroblast growth factor receptor 4 | -7.189 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -4.8046 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.77378 |
| ACOT9 | acyl-CoA thioesterase 9 | -4.54598 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -4.39052 |
| PCNA | proliferating cell nuclear antigen | -4.3083 |
| ADI1 | acireductone dioxygenase 1 | -4.24216 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.23406 |
| TRIB3 | tribbles pseudokinase 3 | -4.20045 |
| DNM1L | dynamin 1-like | -4.07005 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.80024 |
| SPAG4 | sperm associated antigen 4 | -3.28851 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -3.05787 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.81458 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.74704 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.53995 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.49532 |
| SLC35F2 | solute carrier family 35, member F2 | -2.3966 |
| ANKRD10 | ankyrin repeat domain 10 | -2.30471 |
| SLC17A1 | solute carrier family 17 (organic anion transporter), member 1 | -2.28064 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.19115 |
| CSK | c-src tyrosine kinase | -2.17347 |
| ELAC2 | elaC ribonuclease Z 2 | -2.17039 |
| ITIH1 | inter-alpha-trypsin inhibitor heavy chain 1 | -2.16921 |
| UGT2B4 | UDP glucuronosyltransferase 2 family, polypeptide B4 | -2.15207 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.11464 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.08306 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.04683 |
| PDZK1 | PDZ domain containing 1 | -2.02849 |
| SLC17A2 | solute carrier family 17, member 2 | -2.00377 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.00165 |
