CRCGN014_HEPG2_3H:H12 Gene Set
Genes
45 genes differentially expressed following the CRCGN014_HEPG2_3H:H12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
6.21376
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
5.08117
|
|
CBR3
|
carbonyl reductase 3
|
4.53482
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.45978
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.93604
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
3.69471
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.6572
|
|
CSK
|
c-src tyrosine kinase
|
3.53133
|
|
HDGFL3
|
HDGF like 3
|
3.15226
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.1005
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
3.07128
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.02591
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.85827
|
|
SFTPB
|
surfactant protein B
|
2.75251
|
|
CYCS
|
cytochrome c, somatic
|
2.65542
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.62613
|
|
FCHO1
|
FCH domain only 1
|
2.59397
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.54897
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
2.50377
|
|
KIF20A
|
kinesin family member 20A
|
2.43731
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.42564
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.24309
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.23892
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.19426
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.10066
|
|
PIGP
|
phosphatidylinositol glycan anchor biosynthesis, class P
|
2.06443
|
|
F8A2
|
coagulation factor VIII-associated 2
|
2.06389
|
|
GPATCH8
|
G patch domain containing 8
|
2.04328
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-7.37038
|
|
CDC25B
|
cell division cycle 25B
|
-6.37145
|
|
DNM1L
|
dynamin 1-like
|
-6.11483
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-5.10496
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-5.01138
|
|
ISOC1
|
isochorismatase domain containing 1
|
-4.4901
|
|
TSPAN4
|
tetraspanin 4
|
-3.871
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-3.80463
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.67401
|
|
COG2
|
component of oligomeric golgi complex 2
|
-3.62376
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.33124
|
|
CCNB2
|
cyclin B2
|
-2.25142
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.09556
|
|
ITIH1
|
inter-alpha-trypsin inhibitor heavy chain 1
|
-2.0911
|
|
VSTM4
|
V-set and transmembrane domain containing 4
|
-2.07105
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.01722
|
|
MTA1
|
metastasis associated 1
|
-2.00421
|
