CRCGN014_HEPG2_3H:H14 Gene Set
Genes
55 genes differentially expressed following the CRCGN014_HEPG2_3H:H14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
6.60384
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.54837
|
|
CYCS
|
cytochrome c, somatic
|
4.44612
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
4.36677
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
4.01422
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.55031
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
3.51782
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
3.37506
|
|
UBQLN2
|
ubiquilin 2
|
3.35771
|
|
STK10
|
serine/threonine kinase 10
|
3.28069
|
|
FPGS
|
folylpolyglutamate synthase
|
3.264
|
|
CCNA1
|
cyclin A1
|
3.25914
|
|
EPHB2
|
EPH receptor B2
|
3.21747
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.19495
|
|
TEX10
|
testis expressed 10
|
3.15745
|
|
CBR3
|
carbonyl reductase 3
|
2.97919
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.71403
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.70618
|
|
INTS3
|
integrator complex subunit 3
|
2.70122
|
|
ARMCX3
|
armadillo repeat containing, X-linked 3
|
2.49431
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.40718
|
|
TRIB3
|
tribbles pseudokinase 3
|
2.399
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.30126
|
|
FZD1
|
frizzled class receptor 1
|
2.28085
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.25438
|
|
TESK1
|
testis-specific kinase 1
|
2.19766
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.10473
|
|
LCN2
|
lipocalin 2
|
2.09916
|
|
FSD1
|
fibronectin type III and SPRY domain containing 1
|
2.059
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.04427
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
FASTKD5
|
FAST kinase domains 5
|
-5.4644
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-5.34979
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.22754
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-3.61541
|
|
CDC25B
|
cell division cycle 25B
|
-3.59504
|
|
LAP3
|
leucine aminopeptidase 3
|
-3.53798
|
|
VAT1
|
vesicle amine transport 1
|
-3.51142
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.50633
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.3244
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.17345
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.15846
|
|
CCNB2
|
cyclin B2
|
-3.0594
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.04866
|
|
TLR4
|
toll-like receptor 4
|
-2.89083
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.79767
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.72898
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.70004
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.67728
|
|
CSK
|
c-src tyrosine kinase
|
-2.42399
|
|
ZNF586
|
zinc finger protein 586
|
-2.41651
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.27796
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.25215
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.24876
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-2.22812
|
|
SOX9
|
SRY (sex determining region Y)-box 9
|
-2.12214
|
