CRCGN014_HEPG2_3H:H16 Gene Set
Genes
55 genes differentially expressed following the CRCGN014_HEPG2_3H:H16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.83981
|
|
LCN2
|
lipocalin 2
|
3.72106
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.70683
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.67314
|
|
UBQLN2
|
ubiquilin 2
|
3.6512
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
3.58101
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
3.51564
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.446
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.26097
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.1134
|
|
CSK
|
c-src tyrosine kinase
|
2.99956
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.98182
|
|
ILK
|
integrin-linked kinase
|
2.94798
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.8373
|
|
IDE
|
insulin-degrading enzyme
|
2.82353
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.76219
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.72019
|
|
ZNF589
|
zinc finger protein 589
|
2.65577
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
2.42678
|
|
TRIB1
|
tribbles pseudokinase 1
|
2.36853
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.28964
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
2.27187
|
|
FKBP14
|
FK506 binding protein 14, 22 kDa
|
2.23038
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.18129
|
|
SFTPB
|
surfactant protein B
|
2.16989
|
|
CHN1
|
chimerin 1
|
2.12945
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.11986
|
|
STEAP1
|
six transmembrane epithelial antigen of the prostate 1
|
2.08546
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.05239
|
|
E2F5
|
E2F transcription factor 5, p130-binding
|
2.03641
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.04113
|
|
LDHD
|
lactate dehydrogenase D
|
-6.98815
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.91696
|
|
TBC1D31
|
TBC1 domain family, member 31
|
-4.55943
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.19221
|
|
CCNB2
|
cyclin B2
|
-3.57767
|
|
CDC25B
|
cell division cycle 25B
|
-3.49441
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.48699
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.47017
|
|
ZNF586
|
zinc finger protein 586
|
-3.23717
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.22168
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.07286
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.02741
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.01699
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.97512
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.92308
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.89351
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.82283
|
|
DNM1L
|
dynamin 1-like
|
-2.78751
|
|
CD320
|
CD320 molecule
|
-2.74472
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.70268
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.6433
|
|
SNX11
|
sorting nexin 11
|
-2.2886
|
|
RNF167
|
ring finger protein 167
|
-2.2353
|
|
MGRN1
|
mahogunin ring finger 1, E3 ubiquitin protein ligase
|
-2.17567
|
