CRCGN014_HEPG2_3H:H17 Gene Set
Genes
53 genes differentially expressed following the CRCGN014_HEPG2_3H:H17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CBR3
|
carbonyl reductase 3
|
7.08386
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
6.48782
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.92437
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.83152
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.93788
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.89597
|
|
GAA
|
glucosidase, alpha; acid
|
3.43339
|
|
VGLL4
|
vestigial-like family member 4
|
3.13851
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.82455
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.7694
|
|
EPHA3
|
EPH receptor A3
|
2.6951
|
|
E2F2
|
E2F transcription factor 2
|
2.62891
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.62634
|
|
SAA2
|
serum amyloid A2
|
2.53801
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.35379
|
|
MAGEC2
|
melanoma antigen family C2
|
2.32271
|
|
EYA1
|
EYA transcriptional coactivator and phosphatase 1
|
2.29834
|
|
AXIN1
|
axin 1
|
2.29161
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.21336
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.15417
|
|
SIX2
|
SIX homeobox 2
|
2.13531
|
|
RGS9BP
|
regulator of G protein signaling 9 binding protein
|
2.12438
|
|
TPK1
|
thiamin pyrophosphokinase 1
|
2.03907
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.01812
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-10.0
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-7.00816
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-6.57804
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.67653
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.99862
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.9541
|
|
LDHD
|
lactate dehydrogenase D
|
-3.93471
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.88188
|
|
NUP85
|
nucleoporin 85kDa
|
-3.80871
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.79557
|
|
CCNB2
|
cyclin B2
|
-3.65194
|
|
CDR2L
|
cerebellar degeneration-related protein 2-like
|
-3.4756
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.43215
|
|
ZNF586
|
zinc finger protein 586
|
-3.35097
|
|
PSME2
|
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
|
-3.19808
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.01408
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.76012
|
|
WASHC4
|
WASH complex subunit 4
|
-2.53861
|
|
DNM1L
|
dynamin 1-like
|
-2.37962
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.30594
|
|
LLGL2
|
lethal giant larvae homolog 2 (Drosophila)
|
-2.27178
|
|
HMG20B
|
high mobility group 20B
|
-2.22525
|
|
MRPS7
|
mitochondrial ribosomal protein S7
|
-2.18011
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-2.17122
|
|
GNAS
|
GNAS complex locus
|
-2.15304
|
|
SIN3B
|
SIN3 transcription regulator family member B
|
-2.1403
|
|
KCTD2
|
potassium channel tetramerization domain containing 2
|
-2.13857
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.09473
|
|
F3
|
coagulation factor III (thromboplastin, tissue factor)
|
-2.01143
|
