CRCGN014_HEPG2_3H:H19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description mepyramine 39.6 um perturbation at 3 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

40 genes differentially expressed following the CRCGN014_HEPG2_3H:H19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 4.504
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.21626
CCL2 chemokine (C-C motif) ligand 2 3.98568
PPARG peroxisome proliferator-activated receptor gamma 3.9729
CXCL2 chemokine (C-X-C motif) ligand 2 3.50246
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.35012
LYN LYN proto-oncogene, Src family tyrosine kinase 3.34679
STK10 serine/threonine kinase 10 3.28523
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 3.19881
STIMATE STIM activating enhancer 3.16237
VGLL4 vestigial-like family member 4 3.01002
TBP TATA box binding protein 2.98723
HEBP1 heme binding protein 1 2.84427
KIF20A kinesin family member 20A 2.82194
PLSCR3 phospholipid scramblase 3 2.79529
NOTCH1 notch 1 2.78293
AMDHD2 amidohydrolase domain containing 2 2.75585
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.5326
PLSCR1 phospholipid scramblase 1 2.39315
LCN2 lipocalin 2 2.3157
CRTAP cartilage associated protein 2.19619
SFTPB surfactant protein B 2.06846
NPDC1 neural proliferation, differentiation and control, 1 2.03615
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.01483

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -7.60679
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -7.17473
GNAS GNAS complex locus -4.90392
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.73741
LDHD lactate dehydrogenase D -3.09312
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.03265
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -2.85518
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.81202
CCNB1 cyclin B1 -2.72912
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.24556
TAS2R1 taste receptor, type 2, member 1 -2.21782
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -2.20391
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -2.06743
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled -2.03672
NVL nuclear VCP-like -2.03648
POLI polymerase (DNA directed) iota -2.03619