| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | auramine-o 39.6 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
146 genes differentially expressed following the CRCGN014_HEPG2_3H:H21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | 9.99027 |
| DDIT4 | DNA-damage-inducible transcript 4 | 7.69622 |
| EGR1 | early growth response 1 | 7.18742 |
| E2F2 | E2F transcription factor 2 | 6.27374 |
| STIMATE | STIM activating enhancer | 6.05508 |
| JUN | jun proto-oncogene | 5.36105 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 5.18065 |
| MAP7 | microtubule-associated protein 7 | 5.13556 |
| CNPY3 | canopy FGF signaling regulator 3 | 4.76285 |
| IER3 | immediate early response 3 | 4.34942 |
| KIFBP | kinesin family binding protein | 4.2217 |
| HSPA1B | heat shock 70kDa protein 1B | 4.0539 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.94767 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 3.86566 |
| MAMLD1 | mastermind-like domain containing 1 | 3.81484 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 3.55416 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.51918 |
| CSK | c-src tyrosine kinase | 3.50582 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.4674 |
| TRIB1 | tribbles pseudokinase 1 | 3.42475 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.42335 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.33117 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 3.29519 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.27591 |
| STX1A | syntaxin 1A (brain) | 3.24976 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 3.03149 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.96199 |
| LCN2 | lipocalin 2 | 2.92076 |
| MYLK | myosin light chain kinase | 2.89068 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.87022 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 2.84663 |
| SKIC2 | SKI2 subunit of superkiller complex | 2.81375 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | 2.77635 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 2.76302 |
| FOSL1 | FOS-like antigen 1 | 2.75556 |
| PLSCR3 | phospholipid scramblase 3 | 2.74084 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.67219 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 2.61657 |
| HSPB1 | heat shock 27kDa protein 1 | 2.61318 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.55953 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 2.5521 |
| KDM3A | lysine (K)-specific demethylase 3A | 2.55146 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 | 2.51673 |
| SAA2 | serum amyloid A2 | 2.50731 |
| ZFP36 | ZFP36 ring finger protein | 2.5033 |
| HAPLN2 | hyaluronan and proteoglycan link protein 2 | 2.48924 |
| TESK1 | testis-specific kinase 1 | 2.45978 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.44899 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 | 2.41846 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.41055 |
| RRAGA | Ras-related GTP binding A | 2.38973 |
| CLK3 | CDC-like kinase 3 | 2.36985 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 2.36418 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 2.34695 |
| EPCAM | epithelial cell adhesion molecule | 2.34168 |
| AXIN1 | axin 1 | 2.3284 |
| RSF1 | remodeling and spacing factor 1 | 2.32675 |
| KIF20A | kinesin family member 20A | 2.31606 |
| DCAF17 | DDB1 and CUL4 associated factor 17 | 2.28644 |
| DUSP6 | dual specificity phosphatase 6 | 2.26775 |
| CYCS | cytochrome c, somatic | 2.23471 |
| SPAG1 | sperm associated antigen 1 | 2.19516 |
| RBM6 | RNA binding motif protein 6 | 2.18286 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 2.16855 |
| CTC1 | CTS telomere maintenance complex component 1 | 2.12723 |
| KLF6 | Kruppel-like factor 6 | 2.11186 |
| ANXA3 | annexin A3 | 2.11028 |
| ULBP2 | UL16 binding protein 2 | 2.06874 |
| SSX5 | synovial sarcoma, X breakpoint 5 | 2.04885 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like | 2.03581 |
| CCKAR | cholecystokinin A receptor | 2.02375 |
| JADE2 | jade family PHD finger 2 | 2.01358 |
| SCRN1 | secernin 1 | 2.00995 |
| PRB2 | proline-rich protein BstNI subfamily 2 | 2.00716 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| FASTKD5 | FAST kinase domains 5 | -9.20974 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.82926 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -6.73909 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -6.60796 |
| GNAS | GNAS complex locus | -5.04842 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -4.34286 |
| DERA | deoxyribose-phosphate aldolase (putative) | -4.21488 |
| NRIP1 | nuclear receptor interacting protein 1 | -4.12834 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.84706 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -3.7821 |
| COG7 | component of oligomeric golgi complex 7 | -3.56547 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -3.4785 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -3.38628 |
| TLR4 | toll-like receptor 4 | -3.33779 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -3.31288 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.20988 |
| UBE3C | ubiquitin protein ligase E3C | -3.09171 |
| HMOX1 | heme oxygenase 1 | -3.00896 |
| TOMM70 | translocase of outer mitochondrial membrane 70 | -2.95467 |
| HEATR1 | HEAT repeat containing 1 | -2.88167 |
| TUBB6 | tubulin, beta 6 class V | -2.85197 |
| MAT2A | methionine adenosyltransferase II, alpha | -2.83637 |
| ZNF586 | zinc finger protein 586 | -2.80475 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial | -2.78405 |
| GOLT1B | golgi transport 1B | -2.733 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.72857 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.71213 |
| YME1L1 | YME1-like 1 ATPase | -2.66122 |
| PROS1 | protein S (alpha) | -2.61803 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase | -2.57451 |
| FGG | fibrinogen gamma chain | -2.57144 |
| LRRC17 | leucine rich repeat containing 17 | -2.55113 |
| GHITM | growth hormone inducible transmembrane protein | -2.48613 |
| CIRBP | cold inducible RNA binding protein | -2.46418 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -2.43276 |
| SCFD1 | sec1 family domain containing 1 | -2.35164 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -2.34793 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | -2.32304 |
| WDR37 | WD repeat domain 37 | -2.32106 |
| CDC20 | cell division cycle 20 | -2.31401 |
| PGM1 | phosphoglucomutase 1 | -2.2796 |
| CCDC47 | coiled-coil domain containing 47 | -2.26156 |
| STMN1 | stathmin 1 | -2.25384 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | -2.24714 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | -2.21087 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B | -2.20383 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.20053 |
| EIF2B1 | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa | -2.19683 |
| PEX26 | peroxisomal biogenesis factor 26 | -2.18744 |
| TRIB3 | tribbles pseudokinase 3 | -2.16816 |
| TMEM51 | transmembrane protein 51 | -2.15141 |
| CTNNBL1 | catenin, beta like 1 | -2.10526 |
| BLCAP | bladder cancer associated protein | -2.10448 |
| FAM168B | family with sequence similarity 168, member B | -2.09241 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 | -2.08991 |
| KIFC1 | kinesin family member C1 | -2.08318 |
| ITGA1 | integrin, alpha 1 | -2.07052 |
| CTSA | cathepsin A | -2.05337 |
| FGA | fibrinogen alpha chain | -2.05327 |
| RPL32 | ribosomal protein L32 | -2.03628 |
| SMIM10L1 | small integral membrane protein 10 like 1 | -2.03236 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -2.02872 |
| HIRA | histone cell cycle regulator | -2.02545 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.02167 |
| TXNL4B | thioredoxin-like 4B | -2.01563 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -2.01501 |
| NDN | necdin, melanoma antigen (MAGE) family member | -2.00889 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | -2.00677 |
| MRPS22 | mitochondrial ribosomal protein S22 | -2.00656 |
| CTNNBIP1 | catenin, beta interacting protein 1 | -2.00453 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -2.00134 |
