CRCGN014_HEPG2_3H:H22 Gene Set
Genes
50 genes differentially expressed following the CRCGN014_HEPG2_3H:H22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
EPHB2
|
EPH receptor B2
|
4.34162
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.02354
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.6921
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.64376
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.39438
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.35096
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
3.16698
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.00199
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.8728
|
|
CYCS
|
cytochrome c, somatic
|
2.84712
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.77566
|
|
UBQLN2
|
ubiquilin 2
|
2.69566
|
|
RRAGA
|
Ras-related GTP binding A
|
2.69235
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.61189
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.60888
|
|
ANO10
|
anoctamin 10
|
2.58641
|
|
ADGRG1
|
adhesion G protein-coupled receptor G1
|
2.51149
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.44433
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.42071
|
|
ATG7
|
autophagy related 7
|
2.35606
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.34036
|
|
FPGS
|
folylpolyglutamate synthase
|
2.1183
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.08559
|
|
PLEK2
|
pleckstrin 2
|
2.06647
|
|
CCRL2
|
chemokine (C-C motif) receptor-like 2
|
2.03743
|
|
KIFBP
|
kinesin family binding protein
|
2.01004
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-10.0
|
|
LDHD
|
lactate dehydrogenase D
|
-6.22727
|
|
SCAND1
|
SCAN domain containing 1
|
-3.65777
|
|
ELAC2
|
elaC ribonuclease Z 2
|
-3.65498
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.44675
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.4069
|
|
LAP3
|
leucine aminopeptidase 3
|
-3.29772
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-3.01706
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.94246
|
|
ZNF586
|
zinc finger protein 586
|
-2.92652
|
|
WASHC4
|
WASH complex subunit 4
|
-2.86106
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.85117
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.78946
|
|
GOLT1B
|
golgi transport 1B
|
-2.67126
|
|
RNF167
|
ring finger protein 167
|
-2.56387
|
|
GNAS
|
GNAS complex locus
|
-2.56286
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-2.51637
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.42954
|
|
CCNB2
|
cyclin B2
|
-2.21565
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.20719
|
|
SNX11
|
sorting nexin 11
|
-2.12911
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.08527
|
|
FANCI
|
Fanconi anemia, complementation group I
|
-2.06383
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.0099
|