CRCGN014_HEPG2_3H:H23 Gene Set
Genes
37 genes differentially expressed following the CRCGN014_HEPG2_3H:H23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.19026
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.65039
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.14788
|
|
CBR3
|
carbonyl reductase 3
|
4.12764
|
|
MSRA
|
methionine sulfoxide reductase A
|
4.09713
|
|
NOTCH1
|
notch 1
|
3.25104
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.82832
|
|
STK10
|
serine/threonine kinase 10
|
2.73393
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.66568
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.49282
|
|
AXIN1
|
axin 1
|
2.48613
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.45353
|
|
CSK
|
c-src tyrosine kinase
|
2.39765
|
|
YRDC
|
yrdC N(6)-threonylcarbamoyltransferase domain containing
|
2.19901
|
|
CYCS
|
cytochrome c, somatic
|
2.10076
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.95321
|
|
PCNA
|
proliferating cell nuclear antigen
|
-6.82502
|
|
PLK1
|
polo-like kinase 1
|
-4.5385
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.19778
|
|
ZNF586
|
zinc finger protein 586
|
-3.92995
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.64493
|
|
CDC25B
|
cell division cycle 25B
|
-3.61656
|
|
HMG20B
|
high mobility group 20B
|
-3.17528
|
|
CCNB2
|
cyclin B2
|
-3.13753
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.10777
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.08777
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.05364
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.89506
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.84643
|
|
CCNB1
|
cyclin B1
|
-2.78785
|
|
ABCB8
|
ATP-binding cassette, sub-family B (MDR/TAP), member 8
|
-2.70495
|
|
SPAG4
|
sperm associated antigen 4
|
-2.65889
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.448
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.38971
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.27117
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.18265
|
|
DSTN
|
destrin (actin depolymerizing factor)
|
-2.01899
|
