CRCGN014_HEPG2_3H:I02 Gene Set
Genes
36 genes differentially expressed following the CRCGN014_HEPG2_3H:I02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
5.28078
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.06212
|
|
EPHB2
|
EPH receptor B2
|
3.08323
|
|
MEST
|
mesoderm specific transcript
|
3.08085
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.06807
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.91534
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.90175
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.81728
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.63181
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.59036
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
2.49556
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.41802
|
|
HOXA10
|
homeobox A10
|
2.38944
|
|
PFKL
|
phosphofructokinase, liver
|
2.37085
|
|
STXBP2
|
syntaxin binding protein 2
|
2.34321
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.33641
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.27667
|
|
EVL
|
Enah/Vasp-like
|
2.25944
|
|
CAMSAP2
|
calmodulin regulated spectrin-associated protein family, member 2
|
2.23016
|
|
TEX10
|
testis expressed 10
|
2.20727
|
|
SHB
|
Src homology 2 domain containing adaptor protein B
|
2.07559
|
|
MAP7
|
microtubule-associated protein 7
|
2.04671
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-6.80925
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-5.37231
|
|
CDC20
|
cell division cycle 20
|
-3.79597
|
|
LDHD
|
lactate dehydrogenase D
|
-3.61975
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.54618
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.31152
|
|
SPAG4
|
sperm associated antigen 4
|
-3.26401
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.88135
|
|
PGM1
|
phosphoglucomutase 1
|
-2.77805
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.33415
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.22304
|
|
TMEM135
|
transmembrane protein 135
|
-2.1942
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.06848
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
-2.04793
|
