CRCGN014_HEPG2_3H:I03 Gene Set
Genes
41 genes differentially expressed following the CRCGN014_HEPG2_3H:I03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHN1
|
chimerin 1
|
5.63787
|
|
LCN2
|
lipocalin 2
|
5.29695
|
|
MYLK
|
myosin light chain kinase
|
4.18277
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.00733
|
|
EPHB2
|
EPH receptor B2
|
3.89379
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.84817
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
3.84197
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.84175
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.67283
|
|
CYCS
|
cytochrome c, somatic
|
3.55925
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
3.42789
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.24729
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.57562
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.55391
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.48837
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.43912
|
|
RRAGA
|
Ras-related GTP binding A
|
2.29568
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
2.27283
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.20408
|
|
ZMYM2
|
zinc finger, MYM-type 2
|
2.17868
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.11024
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.10993
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-6.66329
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.72797
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.72981
|
|
SPAG4
|
sperm associated antigen 4
|
-4.53811
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.98054
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.85866
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.84056
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.707
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-3.44131
|
|
SNX11
|
sorting nexin 11
|
-3.0189
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.80978
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
-2.60432
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.48197
|
|
PMM2
|
phosphomannomutase 2
|
-2.15721
|
|
NTSR1
|
neurotensin receptor 1 (high affinity)
|
-2.14216
|
|
DMRT1
|
doublesex and mab-3 related transcription factor 1
|
-2.11166
|
|
SOAT2
|
sterol O-acyltransferase 2
|
-2.08716
|
|
DEPDC1
|
DEP domain containing 1
|
-2.0128
|
|
FOXE1
|
forkhead box E1
|
-2.01039
|
