CRCGN014_HEPG2_3H:I04 Gene Set
Genes
45 genes differentially expressed following the CRCGN014_HEPG2_3H:I04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.62114
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
4.79337
|
|
LCN2
|
lipocalin 2
|
4.37083
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.884
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.46877
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.41937
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.28364
|
|
MYLK
|
myosin light chain kinase
|
3.25274
|
|
STXBP2
|
syntaxin binding protein 2
|
3.23669
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.17697
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.11907
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.06483
|
|
CBR3
|
carbonyl reductase 3
|
3.05633
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.90637
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.81583
|
|
HOXA10
|
homeobox A10
|
2.79763
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.72981
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.60426
|
|
CYBA
|
cytochrome b-245, alpha polypeptide
|
2.35171
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.33255
|
|
NOL9
|
nucleolar protein 9
|
2.26348
|
|
KIF5C
|
kinesin family member 5C
|
2.2609
|
|
TSPAN14
|
tetraspanin 14
|
2.22
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.21697
|
|
GPATCH8
|
G patch domain containing 8
|
2.15106
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.63479
|
|
RAI14
|
retinoic acid induced 14
|
-4.38713
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.72203
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.47493
|
|
SNX11
|
sorting nexin 11
|
-3.18928
|
|
TLR4
|
toll-like receptor 4
|
-3.06876
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.03499
|
|
GRB7
|
growth factor receptor-bound protein 7
|
-2.94878
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.85595
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.69972
|
|
ZNF586
|
zinc finger protein 586
|
-2.66296
|
|
DSG2
|
desmoglein 2
|
-2.5158
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.50523
|
|
CSK
|
c-src tyrosine kinase
|
-2.45138
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-2.42313
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.40037
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.31652
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.31597
|
|
GNAS
|
GNAS complex locus
|
-2.09438
|
|
NEDD9
|
neural precursor cell expressed, developmentally down-regulated 9
|
-2.06227
|
