CRCGN014_HEPG2_3H:I05 Gene Set
Genes
47 genes differentially expressed following the CRCGN014_HEPG2_3H:I05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
10.0
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.19685
|
|
STIMATE
|
STIM activating enhancer
|
5.80855
|
|
EPN2
|
epsin 2
|
4.37474
|
|
EPHA3
|
EPH receptor A3
|
4.10393
|
|
LCN2
|
lipocalin 2
|
3.7973
|
|
UBQLN2
|
ubiquilin 2
|
3.70336
|
|
JADE2
|
jade family PHD finger 2
|
3.55765
|
|
CBR3
|
carbonyl reductase 3
|
3.29815
|
|
CSK
|
c-src tyrosine kinase
|
3.22072
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.2039
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.1
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.99345
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.82119
|
|
ZNF589
|
zinc finger protein 589
|
2.78107
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.75969
|
|
STK10
|
serine/threonine kinase 10
|
2.7037
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.5067
|
|
CHN1
|
chimerin 1
|
2.44086
|
|
PFAS
|
phosphoribosylformylglycinamidine synthase
|
2.43986
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.3103
|
|
SLC5A5
|
solute carrier family 5 (sodium/iodide cotransporter), member 5
|
2.26719
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.21925
|
|
NUCB2
|
nucleobindin 2
|
2.18217
|
|
SERPINB3
|
serpin peptidase inhibitor, clade B (ovalbumin), member 3
|
2.10642
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.10436
|
|
PGLYRP4
|
peptidoglycan recognition protein 4
|
2.0036
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-8.10614
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-6.58923
|
|
LDHD
|
lactate dehydrogenase D
|
-6.0511
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.83359
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
-3.65573
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.44445
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.1831
|
|
SPAG4
|
sperm associated antigen 4
|
-3.01014
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.00097
|
|
GNAS
|
GNAS complex locus
|
-2.75542
|
|
CCNB2
|
cyclin B2
|
-2.62825
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.62078
|
|
CDC25B
|
cell division cycle 25B
|
-2.56895
|
|
PLK1
|
polo-like kinase 1
|
-2.51017
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.46176
|
|
ZNF586
|
zinc finger protein 586
|
-2.44389
|
|
CCNB1
|
cyclin B1
|
-2.4202
|
|
EPCAM
|
epithelial cell adhesion molecule
|
-2.18478
|
|
CHPF
|
chondroitin polymerizing factor
|
-2.16383
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.13186
|
