CRCGN014_HEPG2_3H:I08 Gene Set
Genes
47 genes differentially expressed following the CRCGN014_HEPG2_3H:I08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
8.75988
|
|
UBQLN2
|
ubiquilin 2
|
8.33057
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
7.41497
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.47718
|
|
MAP7
|
microtubule-associated protein 7
|
5.36274
|
|
E2F2
|
E2F transcription factor 2
|
4.89904
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
4.82514
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.60053
|
|
STIMATE
|
STIM activating enhancer
|
4.56488
|
|
NOTCH1
|
notch 1
|
4.52807
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
4.19618
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.03501
|
|
CHN1
|
chimerin 1
|
3.95632
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.43936
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.11087
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.94438
|
|
EPHB2
|
EPH receptor B2
|
2.88577
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.88465
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.72583
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.34141
|
|
VGLL4
|
vestigial-like family member 4
|
2.33746
|
|
CYCS
|
cytochrome c, somatic
|
2.25407
|
|
ANGPTL2
|
angiopoietin-like 2
|
2.17842
|
|
SHB
|
Src homology 2 domain containing adaptor protein B
|
2.13958
|
|
GPATCH8
|
G patch domain containing 8
|
2.13613
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.12261
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.03412
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-8.22929
|
|
PCNA
|
proliferating cell nuclear antigen
|
-6.38746
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-5.26196
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-4.94913
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-4.60156
|
|
CCNB2
|
cyclin B2
|
-4.55119
|
|
TLR4
|
toll-like receptor 4
|
-4.29918
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.83377
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.37415
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.04425
|
|
SPAG4
|
sperm associated antigen 4
|
-3.0362
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.02775
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.8275
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.7575
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.41738
|
|
REEP5
|
receptor accessory protein 5
|
-2.32551
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
-2.31578
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.20139
|
|
COPG1
|
coatomer protein complex, subunit gamma 1
|
-2.16221
|
|
IPO13
|
importin 13
|
-2.14605
|
