CRCGN014_HEPG2_3H:I09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-benzyl 2-butyl phthalate 21.13 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

53 genes differentially expressed following the CRCGN014_HEPG2_3H:I09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 6.40499
MAP7 microtubule-associated protein 7 5.33973
NOTCH1 notch 1 4.66196
CCL2 chemokine (C-C motif) ligand 2 4.62216
CSK c-src tyrosine kinase 3.6905
HEBP1 heme binding protein 1 3.55698
AXIN1 axin 1 3.17881
TIAM1 T-cell lymphoma invasion and metastasis 1 2.86565
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.71334
CXCL2 chemokine (C-X-C motif) ligand 2 2.68713
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.60184
CTSL cathepsin L 2.60058
EVL Enah/Vasp-like 2.56926
ZBTB18 zinc finger and BTB domain containing 18 2.41188
EGF epidermal growth factor 2.33382
KIF20A kinesin family member 20A 2.29006
NUP133 nucleoporin 133kDa 2.23665
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.19019
BAMBI BMP and activin membrane-bound inhibitor 2.17446
CIAO3 cytosolic iron-sulfur assembly component 3 2.12476
DIPK1A divergent protein kinase domain 1A 2.11246
CCNA1 cyclin A1 2.10643
TMEM134 transmembrane protein 134 2.05829

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -7.5509
GTPBP8 GTP-binding protein 8 (putative) -4.83747
COG7 component of oligomeric golgi complex 7 -4.8257
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.63134
OXA1L oxidase (cytochrome c) assembly 1-like -4.60864
ZNF586 zinc finger protein 586 -3.24143
EIF5 eukaryotic translation initiation factor 5 -3.02419
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.02322
HSPA8 heat shock 70kDa protein 8 -3.01033
NRIP1 nuclear receptor interacting protein 1 -2.69946
SMC4 structural maintenance of chromosomes 4 -2.64377
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -2.59674
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.58416
PRPF4 pre-mRNA processing factor 4 -2.50996
SLC35F2 solute carrier family 35, member F2 -2.47573
WASHC4 WASH complex subunit 4 -2.40477
TRIM56 tripartite motif containing 56 -2.31942
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -2.28624
NONO non-POU domain containing, octamer-binding -2.26827
ATF7IP2 activating transcription factor 7 interacting protein 2 -2.24551
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.18106
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.17872
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.12757
RNF167 ring finger protein 167 -2.10427
BCL7C B-cell CLL/lymphoma 7C -2.09946
PINLYP phospholipase A2 inhibitor and LY6/PLAUR domain containing -2.09169
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -2.08522
ASXL2 additional sex combs like transcriptional regulator 2 -2.04993
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -2.01058
AKIP1 A kinase (PRKA) interacting protein 1 -2.00696