| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sulforaphane 19.97 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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106 genes differentially expressed following the CRCGN014_HEPG2_3H:I14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | 9.82145 |
| DDIT4 | DNA-damage-inducible transcript 4 | 9.47177 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 7.15448 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.83226 |
| PPARG | peroxisome proliferator-activated receptor gamma | 6.54931 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 6.43286 |
| UBQLN2 | ubiquilin 2 | 6.03728 |
| TRIB3 | tribbles pseudokinase 3 | 5.06759 |
| BAG3 | BCL2-associated athanogene 3 | 4.40678 |
| FOSL1 | FOS-like antigen 1 | 4.06592 |
| HMOX1 | heme oxygenase 1 | 3.89795 |
| HSPA1B | heat shock 70kDa protein 1B | 3.85129 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.76148 |
| MAMLD1 | mastermind-like domain containing 1 | 3.71398 |
| TXNRD1 | thioredoxin reductase 1 | 3.71105 |
| EGR1 | early growth response 1 | 3.63841 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 3.61914 |
| TRIB1 | tribbles pseudokinase 1 | 3.51779 |
| CBR3 | carbonyl reductase 3 | 3.42438 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 3.24466 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 3.13226 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.94704 |
| ADAM10 | ADAM metallopeptidase domain 10 | 2.87973 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 2.86003 |
| ANKRD10 | ankyrin repeat domain 10 | 2.84743 |
| EPHA3 | EPH receptor A3 | 2.80134 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.76926 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 2.76763 |
| EPHB2 | EPH receptor B2 | 2.70085 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 2.67993 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.67537 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.65814 |
| CCNA1 | cyclin A1 | 2.6418 |
| ABHD4 | abhydrolase domain containing 4 | 2.62929 |
| GALE | UDP-galactose-4-epimerase | 2.58696 |
| TRAM2 | translocation associated membrane protein 2 | 2.56907 |
| JMJD6 | jumonji domain containing 6 | 2.5645 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.51062 |
| LOC128125814 | uncharacterized LOC128125814 | 2.45708 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.35657 |
| KLHL9 | kelch-like family member 9 | 2.35591 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 2.304 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 2.25883 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 2.15239 |
| IPP | intracisternal A particle-promoted polypeptide | 2.12478 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.10214 |
| MAP7 | microtubule-associated protein 7 | 2.1017 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 2.09875 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 2.09405 |
| GTF2E2 | general transcription factor IIE, polypeptide 2, beta 34kDa | 2.09199 |
| SLC75A1 | solute carrier family 75 member 1 | 2.0849 |
| VSTM4 | V-set and transmembrane domain containing 4 | 2.06684 |
| TAC4 | tachykinin 4 (hemokinin) | 2.03873 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 2.03619 |
| NUP37 | nucleoporin 37kDa | 2.0135 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -6.53363 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.76996 |
| GNAS | GNAS complex locus | -5.38437 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -4.97457 |
| COG2 | component of oligomeric golgi complex 2 | -4.18745 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.99675 |
| PCNA | proliferating cell nuclear antigen | -3.82983 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -3.75015 |
| MTA1 | metastasis associated 1 | -3.7014 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -3.62296 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.56163 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -3.49065 |
| TXNDC9 | thioredoxin domain containing 9 | -3.44102 |
| MSH6 | mutS homolog 6 | -3.35305 |
| SOX4 | SRY (sex determining region Y)-box 4 | -3.34946 |
| ELAC2 | elaC ribonuclease Z 2 | -3.24295 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.07772 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.05199 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.89521 |
| STMN1 | stathmin 1 | -2.77221 |
| TUBB6 | tubulin, beta 6 class V | -2.70598 |
| NISCH | nischarin | -2.66524 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -2.61914 |
| CCNB2 | cyclin B2 | -2.60504 |
| BMP4 | bone morphogenetic protein 4 | -2.51972 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -2.51363 |
| HPS6 | Hermansky-Pudlak syndrome 6 | -2.50594 |
| MTFR1 | mitochondrial fission regulator 1 | -2.48891 |
| POGLUT1 | protein O-glucosyltransferase 1 | -2.4411 |
| SPEG | SPEG complex locus | -2.43084 |
| TBC1D31 | TBC1 domain family, member 31 | -2.38495 |
| WBP4 | WW domain binding protein 4 | -2.32982 |
| ISOC1 | isochorismatase domain containing 1 | -2.31559 |
| IMMT | inner membrane protein, mitochondrial | -2.30535 |
| SKIC2 | SKI2 subunit of superkiller complex | -2.27147 |
| FAM50B | family with sequence similarity 50, member B | -2.24913 |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 | -2.23914 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -2.23335 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -2.20016 |
| MAT2A | methionine adenosyltransferase II, alpha | -2.17712 |
| MVP | major vault protein | -2.1739 |
| ANAPC2 | anaphase promoting complex subunit 2 | -2.17136 |
| SLC35G2 | solute carrier family 35, member G2 | -2.15945 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.15542 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 | -2.14123 |
| PRPF4 | pre-mRNA processing factor 4 | -2.13141 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -2.09682 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -2.06976 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | -2.04627 |
| DUSP14 | dual specificity phosphatase 14 | -2.023 |
| NUP85 | nucleoporin 85kDa | -2.01211 |
