CRCGN014_HEPG2_3H:I18 Gene Set
Genes
38 genes differentially expressed following the CRCGN014_HEPG2_3H:I18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.93025
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
6.83768
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
5.48626
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.70032
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
3.81639
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.74824
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.6104
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.48577
|
|
STK10
|
serine/threonine kinase 10
|
3.40736
|
|
RPL39L
|
ribosomal protein L39-like
|
3.38749
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.27686
|
|
NOTCH1
|
notch 1
|
3.24012
|
|
NFATC3
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
|
2.73308
|
|
SFTPB
|
surfactant protein B
|
2.70345
|
|
IDE
|
insulin-degrading enzyme
|
2.60386
|
|
TBC1D10C
|
TBC1 domain family, member 10C
|
2.57667
|
|
UBQLN2
|
ubiquilin 2
|
2.56635
|
|
CHN1
|
chimerin 1
|
2.5515
|
|
USP6NL
|
USP6 N-terminal like
|
2.17398
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.10111
|
|
TBP
|
TATA box binding protein
|
2.07644
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.0409
|
|
CHEK2
|
checkpoint kinase 2
|
2.03507
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.03
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.16542
|
|
CCNB2
|
cyclin B2
|
-6.21213
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.48896
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.31216
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.17967
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.10893
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-2.85253
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.78398
|
|
PLK1
|
polo-like kinase 1
|
-2.76413
|
|
TLR4
|
toll-like receptor 4
|
-2.68594
|
|
WASHC4
|
WASH complex subunit 4
|
-2.58004
|
|
CCNB1
|
cyclin B1
|
-2.21858
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.20285
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.06019
|
