CRCGN014_HEPG2_3H:I20 Gene Set
Genes
31 genes differentially expressed following the CRCGN014_HEPG2_3H:I20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.36557
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.30087
|
|
LCN2
|
lipocalin 2
|
4.01508
|
|
CAPN1
|
calpain 1, (mu/I) large subunit
|
3.83202
|
|
MYLK
|
myosin light chain kinase
|
3.82673
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.50219
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.15976
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.96662
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.56988
|
|
KLHL21
|
kelch-like family member 21
|
2.5549
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.53209
|
|
SKIC2
|
SKI2 subunit of superkiller complex
|
2.42043
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.33534
|
|
KLHL9
|
kelch-like family member 9
|
2.22949
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.22289
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.16442
|
|
ZBTB18
|
zinc finger and BTB domain containing 18
|
2.058
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.182
|
|
CCNB2
|
cyclin B2
|
-5.82117
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-5.53047
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.71256
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.53627
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.20694
|
|
GNAS
|
GNAS complex locus
|
-2.76813
|
|
LDHD
|
lactate dehydrogenase D
|
-2.5431
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.48869
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.44161
|
|
CAB39
|
calcium binding protein 39
|
-2.31681
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.09082
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.05303
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.03382
|
