CRCGN014_HEPG2_3H:I21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosopiperidine 39.8 um perturbation at 3 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

33 genes differentially expressed following the CRCGN014_HEPG2_3H:I21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 6.613
CHMP6 charged multivesicular body protein 6 6.08582
BACE2 beta-site APP-cleaving enzyme 2 5.42049
UBQLN2 ubiquilin 2 5.22547
RPL39L ribosomal protein L39-like 4.7803
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.4067
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 4.26651
MYLK myosin light chain kinase 3.6797
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.57691
ABHD6 abhydrolase domain containing 6 3.45668
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.30536
MOK MOK protein kinase 3.20725
CXCL2 chemokine (C-X-C motif) ligand 2 2.84435
GPATCH8 G patch domain containing 8 2.66985
RRAGA Ras-related GTP binding A 2.58887
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.35567
CCNH cyclin H 2.24739
CDK19 cyclin-dependent kinase 19 2.24444
SFTPB surfactant protein B 2.09353
STIMATE STIM activating enhancer 2.02722

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -7.9909
ZNF586 zinc finger protein 586 -7.95083
CCNB2 cyclin B2 -7.714
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.74532
OXA1L oxidase (cytochrome c) assembly 1-like -3.80188
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.22931
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.89851
TXNDC9 thioredoxin domain containing 9 -2.88958
NRIP1 nuclear receptor interacting protein 1 -2.76034
TM9SF3 transmembrane 9 superfamily member 3 -2.57592
HSPA8 heat shock 70kDa protein 8 -2.3883
TLCD3A TLC domain containing 3A -2.33562
RNF167 ring finger protein 167 -2.12738