| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | o,o-diethyl o-(4-nitrophenyl) thiophosphate 21.22 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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75 genes differentially expressed following the CRCGN014_HEPG2_3H:I23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 6.11811 |
| LCN2 | lipocalin 2 | 4.85359 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.82461 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.61167 |
| NOTCH1 | notch 1 | 4.10588 |
| ZNF589 | zinc finger protein 589 | 3.72714 |
| MYLK | myosin light chain kinase | 3.63359 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 3.50126 |
| MELK | maternal embryonic leucine zipper kinase | 3.48227 |
| C5 | complement component 5 | 3.47776 |
| MAP7 | microtubule-associated protein 7 | 3.37657 |
| PLSCR1 | phospholipid scramblase 1 | 3.35349 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.25608 |
| PTK2 | protein tyrosine kinase 2 | 3.22536 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 3.14493 |
| SHB | Src homology 2 domain containing adaptor protein B | 3.12898 |
| E2F2 | E2F transcription factor 2 | 3.08142 |
| EPHA3 | EPH receptor A3 | 3.0306 |
| TWF2 | twinfilin actin binding protein 2 | 2.90969 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.7816 |
| CEP57 | centrosomal protein 57kDa | 2.7538 |
| ADRB2 | adrenoceptor beta 2, surface | 2.71437 |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa | 2.70706 |
| UBQLN2 | ubiquilin 2 | 2.68968 |
| ABHD6 | abhydrolase domain containing 6 | 2.68126 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.67568 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.6555 |
| EVL | Enah/Vasp-like | 2.62818 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.61001 |
| SOX2 | SRY (sex determining region Y)-box 2 | 2.60853 |
| CYCS | cytochrome c, somatic | 2.60639 |
| VGLL4 | vestigial-like family member 4 | 2.58795 |
| MEST | mesoderm specific transcript | 2.36564 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 2.30933 |
| TESK1 | testis-specific kinase 1 | 2.19655 |
| TEX10 | testis expressed 10 | 2.13558 |
| ICAM1 | intercellular adhesion molecule 1 | 2.12662 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 2.12014 |
| GTF2E2 | general transcription factor IIE, polypeptide 2, beta 34kDa | 2.04928 |
| MUS81 | MUS81 structure-specific endonuclease subunit | 2.04824 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -7.89721 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -5.22407 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.97101 |
| UGDH | UDP-glucose 6-dehydrogenase | -4.76814 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.50409 |
| SLC35F2 | solute carrier family 35, member F2 | -4.30435 |
| GNAS | GNAS complex locus | -4.23135 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.08733 |
| CDC25B | cell division cycle 25B | -3.98564 |
| LDHD | lactate dehydrogenase D | -3.9308 |
| TLR4 | toll-like receptor 4 | -3.47635 |
| RAI14 | retinoic acid induced 14 | -3.03569 |
| CDK1 | cyclin-dependent kinase 1 | -3.00625 |
| ZNF586 | zinc finger protein 586 | -2.86652 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -2.73289 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.62879 |
| NVL | nuclear VCP-like | -2.58893 |
| TRAPPC3 | trafficking protein particle complex 3 | -2.5679 |
| APIP | APAF1 interacting protein | -2.50817 |
| HEATR1 | HEAT repeat containing 1 | -2.45772 |
| LAGE3 | L antigen family, member 3 | -2.44713 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.34281 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -2.32764 |
| LYRM1 | LYR motif containing 1 | -2.18524 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -2.18278 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 | -2.16448 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) | -2.12376 |
| PARP2 | poly (ADP-ribose) polymerase 2 | -2.08921 |
| FOXJ3 | forkhead box J3 | -2.0796 |
| AGO1 | argonaute RISC catalytic component 1 | -2.07552 |
| TXNDC9 | thioredoxin domain containing 9 | -2.07513 |
| WDR7 | WD repeat domain 7 | -2.07281 |
| TSPAN3 | tetraspanin 3 | -2.06679 |
| NCOA6 | nuclear receptor coactivator 6 | -2.05376 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -2.0139 |
